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Merck
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重要文件

913375

Sigma-Aldrich

支化聚乙烯亚胺溶液

2mg/mL aqueous solution, suitable for biomedical research

同義詞:

PEI溶液

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About This Item

線性公式:
H(NHCH2CH2)mNH2
CAS號碼:
MDL號碼:
分類程式碼代碼:
12352116
NACRES:
NA.23

品質等級

形狀

liquid

濃度

2 mg/mL

顏色

colorless to pale yellow

儲存溫度

2-8°C

SMILES 字串

N1CC1

InChI

1S/C2H5N/c1-2-3-1/h3H,1-2H2

InChI 密鑰

NOWKCMXCCJGMRR-UHFFFAOYSA-N

應用

高分子量分支PEI由于其在多种细胞中的高转染效率而通常用于基因递送。分支PEI已用于在体外和体内成功递送遗传物质,同时通过DNA络合保持低细胞毒性。

儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析證明 (COA)

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W T Godbey et al.
Journal of biomedical materials research, 45(3), 268-275 (1999-07-09)
Poly(ethylenimine) (PEI) samples of various molecular weights and pHs were used to transfect endothelial cells to achieve levels of gene expression for comparison. PEIs with nominal molecular weights of 600, 1200, 1800, 10,000, and 70,000 Da were examined at pHs
O Boussif et al.
Proceedings of the National Academy of Sciences of the United States of America, 92(16), 7297-7301 (1995-08-01)
Several polycations possessing substantial buffering capacity below physiological pH, such as lipopolyamines and polyamidoamine polymers, are efficient transfection agents per se--i.e., without the addition of cell targeting or membrane-disruption agents. This observation led us to test the cationic polymer polyethylenimine

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