跳轉至內容
Merck
全部照片(2)

文件

909300

Sigma-Aldrich

Carboxylic acid-poly(ethylene glycol)-b-poly(D,L lactide)

PEG average Mn 5,000, PDLA average Mn 16,000

同義詞:

COOH-PEG-PDLA, COOH-PEG-PLA, Carboxylic acid PEG-PDLA, Carboxylic acid-PEG-PLA

登入查看組織和合約定價


About This Item

線性公式:
HO(C3H4O2)m(C2H4O)nC2H3O2
分類程式碼代碼:
12352106
NACRES:
NA.23

形狀

powder or chunks

分子量

PDLA average Mn 16,000 (by NMR)
PEG average Mn 5,000 (by NMR)

顏色

white to tan

儲存溫度

−20°C

尋找類似的產品? 前往 產品比較指南

應用

Carboxylic acid-poly(ethylene glycol)-b-poly(D,L lactide) is a functionalized, amphiphilic, diblock copolymer composed of a hydrophilic PEG block and a hydrophobic PLA block. These biodegradable, biocompatible polymers can self-assemble to form nanoparticles, such as micelles and polymersomes, in both aqueous and non-aqueous media. Due to these properties, these polymers are widely used in polymeric nanoparticle formulation to achieve controlled and targeted delivery of therapeutic agents (e.g. APIs, genetic material, peptides, vaccines, and antibiotics). The carboxylic acid functional group on the PEG chain enables rapid and facile surface functionalization, allowing for these materials to be used in applications such as targeted drug delivery.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。

已經擁有該產品?

您可以在文件庫中找到最近購買的產品相關文件。

存取文件庫

Ren Zhong Xiao et al.
International journal of nanomedicine, 5, 1057-1065 (2010-12-21)
Due to their small particle size and large and modifiable surface, nanoparticles have unique advantages compared with other drug carriers. As a research focus in recent years, polyethylene glycol-polylactic acid (PEG-PLA) block copolymer and its end-group derivative nanoparticles can enhance
R Gref et al.
Science (New York, N.Y.), 263(5153), 1600-1603 (1994-03-18)
Injectable nanoparticulate carriers have important potential applications such as site-specific drug delivery or medical imaging. Conventional carriers, however, cannot generally be used because they are eliminated by the reticulo-endothelial system within seconds or minutes after intravenous injection. To address these

文章

Professor Robert K. Prud’homme introduces flash nanoprecipitation (FNP) for nanoparticle fabrication, which is a scalable, rapid mixing process for nanoparticle formulations.

我們的科學家團隊在所有研究領域都有豐富的經驗,包括生命科學、材料科學、化學合成、色譜、分析等.

聯絡技術服務