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Merck
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重要文件

806382

Sigma-Aldrich

N -异丙基丙烯酰胺

carboxylic acid terminated

同義詞:

NIPAM 聚合物, PNIPAM, 功能化聚(N-异丙基丙烯酰胺)

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About This Item

經驗公式(希爾表示法):
C4H7O2(C6H11NO)nH
分類程式碼代碼:
12162002
NACRES:
NA.23

形狀

powder

分子量

average Mw 10,000

蛋白質二硫鍵異構酶

<1.3

儲存溫度

2-8°C

應用

PolyNIPAM 是一种刺激反应性聚合物。 低 PDI 意味着链长的分布窄,这通常会导致更好的可重复性。该聚合物用于开发热敏涂层的微米/纳米材料,包括热响应性聚合物药物递送系统。羧酸官能团可用于使多种生物分子与聚合物链缀合。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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W L Hinrichs et al.
Journal of controlled release : official journal of the Controlled Release Society, 60(2-3), 249-259 (1999-07-30)
Copolymers of 2-(dimethylamino) ethyl methacrylate (DMAEMA) and N-isopropylacryl amide (NIPAAm) of various monomer ratios and molecular weights were evaluated as carrier systems for DNA delivery. All copolymers, even with a low DMAEMA content of 15 mol%, were able to bind
Ravin Narain et al.
Langmuir : the ACS journal of surfaces and colloids, 23(11), 6299-6304 (2007-04-25)
We describe here the synthesis of 10 nm, monodisperse, iron oxide nanoparticles that we have coated with temperature-sensitive, biotinylated p(NIPAAm) (b-PNIPAAm). The PNIPAAm was prepared by the reversible addition fragmentation chain transfer polymerization (RAFT), and one end was biotinylated with
J E Chung et al.
Journal of controlled release : official journal of the Controlled Release Society, 62(1-2), 115-127 (1999-10-16)
To achieve a combination of spatial specificity in a passive manner with a stimuli-responsive targeting mechanism, a temperature-responsive polymeric micelle is prepared using block copolymers of (poly(N-isopropylacrylamide-b-butylmethacrylate) (PIPAAm-PBMA)). The micelle inner core formed by self-aggregates of PBMA segments successfully loaded

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