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Merck
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重要文件

803561

Sigma-Aldrich

BMOE(双马来酰亚胺乙烷)

同義詞:

1,1′-ethane-1,2-diylbis(1H-pyrrole-2,5-dione), N,N′-Ethylenebismaleimide, BMOE, Ethylenebismaleimide

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About This Item

經驗公式(希爾表示法):
C10H8N2O4
CAS號碼:
分子量::
220.18
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.22
形狀:
powder

形狀

powder

分子量

220.18

反應適用性

reagent type: cross-linking reagent

儲存條件

desiccated

溶解度

DMSO or DMF: soluble

運輸包裝

ambient

儲存溫度

2-8°C

SMILES 字串

O=C(C=CC1=O)N1CCN2C(C=CC2=O)=O

InChI

1S/C10H8N2O4/c13-7-1-2-8(14)11(7)5-6-12-9(15)3-4-10(12)16/h1-4H,5-6H2

InChI 密鑰

PUKLCKVOVCZYKF-UHFFFAOYSA-N

一般說明

BMOE、BMB和BMH是同型双功能马来酰亚胺交联剂,可用于巯基(-SH)之间的缀合。此类双马来酰亚胺交联剂通常用于探索和表征蛋白质结构(即,寡聚化)或蛋白质相互作用。因为BMOE、BMB和BMH具有相同的反应性但长度不同,因此这三种试剂在蛋白质寡聚体中位点之间形成交联或相互作用的相对成功性可有助于确定分子内和分子间的距离。

特點和優勢

  • 反应基团:马来酰亚胺(两端)
  • 反应性基团:巯基
  • 短(8.0Å)巯基-巯基交联剂,由马来酰亚胺基团和7-原子间隔臂组成
  • 最短的双马来酰亚胺交联剂,可用于近距离交联
  • 水不溶性 - 需首先溶于DMF或DMSO中,然后加入含水反应缓冲液中
  • 不可剪切

注意

这种产品对湿气很敏感。小瓶包装在带有干燥剂的可再密封袋中,以减少湿气接触。冷藏后,打开前将小瓶平衡至室温,以减少小瓶内的冷凝。制备新的溶液。不建议储存原液。使用后,将小瓶放回可重新密封的袋子中。封闭袋子,在推荐的温度下储存产品。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析證明 (COA)

Lot/Batch Number

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