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Merck
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745774

Sigma-Aldrich

8-Amino-1-octanethiol hydrochloride

95%

同義詞:

8-Mercaptooctylamine hydrochloride

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About This Item

經驗公式(希爾表示法):
C8H19NS · HCl
CAS號碼:
分子量::
197.77
MDL號碼:
分類程式碼代碼:
12352103
PubChem物質ID:
NACRES:
NA.23

化驗

95%

形狀

solid

mp

158-163 °C

儲存溫度

2-8°C

SMILES 字串

SCCCCCCCCN.Cl

InChI

1S/C8H19NS.ClH/c9-7-5-3-1-2-4-6-8-10;/h10H,1-9H2;1H

InChI 密鑰

CCWZBRKMJBSNQS-UHFFFAOYSA-N

一般說明

8-Amino-1-octanethiol hydrochloride (8-AOT) is an amine based alkanethiol that can be used as a self-assembled monolayer (SAM) on a variety of surfaces. It facilitates the immobilization of surface atoms and controls the physiochemical properties of the substrate.

應用

8-AOT can be used in the surface functionalization of gold electrodes for the trace analysis of oligonucleotide using poly nucleic acid (PNA) based ion-channel sensors. It can be used in the fabrication of peptide microarray for surface plasmon resonance based screening of protein kinase activity.
Self Assembly Molecules (SAMs); the amino group is usually modified using amine-reactive materials; such as proteins or biomaterials; to functionalize the gold surface. It is used for biosenors with large amounts of immobilized protein and suppression of nonspecific adsorption

象形圖

Environment

訊號詞

Warning

危險聲明

防範說明

危險分類

Aquatic Acute 1 - Aquatic Chronic 1

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Jolene L Lau et al.
ACS nano, 5(10), 7722-7729 (2011-09-09)
A high-affinity RNA aptamer (K(d) = 50 nM) was efficiently identified by SELEX against a heteroaryldihydropyrimidine structure, chosen as a representative drug-like molecule with no cross reactivity with mammalian or bacterial cells. This aptamer, its weaker-binding variants, and a known
Tillmann Utesch et al.
Langmuir : the ACS journal of surfaces and colloids, 28(13), 5761-5769 (2012-03-06)
Sulfite oxidase (SO) is an enzyme catalyzing the terminal step of the metabolism of sulfur-containing amino acids that is essential for almost all living organisms. The catalytic activity of SO in vertebrates strongly depends on the efficiency of the intramolecular
Trace analysis of an oligonucleotide with a specific sequence using PNA-based ion-channel sensors
Aoki H and Umezawa Y
Analyst, 128(6), 681-685 (2003)
Evaluation of protein kinase activities of cell lysates using peptide microarrays based on surface plasmon resonance imaging
Mori T, et al.
Analytical Biochemistry, 375(2), 223-231 (2008)
Photooxidation of amine-terminated self-assembled monolayers on gold
Lee S, et al.
The Journal of Physical Chemistry C, 114(23), 10512-10519 (2010)

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