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Merck
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重要文件

541850

Sigma-Aldrich

2-氨基-4-氯苯硫醇

96%

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About This Item

線性公式:
H2NC6H3(Cl)SH
CAS號碼:
分子量::
159.64
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

化驗

96%

mp

56-61 °C (lit.)

官能基

chloro

SMILES 字串

Nc1cc(Cl)ccc1S

InChI

1S/C6H6ClNS/c7-4-1-2-6(9)5(8)3-4/h1-3,9H,8H2

InChI 密鑰

NGIRMPARLVGMPX-UHFFFAOYSA-N

一般說明

2-Amino-4-chlorobenzenethiol reacts with aromatic aldehydes and cyclohexanecarboxaldehyde to afford the corresponding thiazole and thiazoline derivatives. It undergoes oxidation in the presence of 1-n-butyl-3-methylimidazolium methylselenite, [bmim][SeO2(OCH3)] to form the corresponding symmetrical disulfide.

應用

2-Amino-4-chlorobenzenethiol may be used in the synthesis of:
  • 2,3-dihydro-1,5-benzothiazepin-4-(5H)-ones
  • 8-chloro-1-azaphenothiazine
  • 5-chloro-2-(4-methoxyphenyl)-2,3-dihydro-1,3,2-benzothiazaphosphole 2-sulfide

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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分析證明 (COA)

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Base-free oxidation of thiols to disulfides using selenium ionic liquid.
Thurow S, et al.
Tetrahedron Letters, 52(5), 640-643 (2011)
Brajendra S Kusmariya et al.
Journal of molecular modeling, 21(11), 278-278 (2015-10-07)
Three mononuclear coordination complexes of Co(II), Ni(II), and Cu(II) have been synthesized from 2,4-dichloro-6-{(E)-[(5-chloro-2-sulfanylphenyl)imino]methyl}phenol ligand (H 2 L) obtained by simple condensation reaction of 3,5-dichloro-2-hydroxybenzaldehyde and 2-amino-4-chlorobenzenethiol and characterized by elemental analysis, spectral (FT-IR, electronic, and (1)H-NMR), molar conductance, thermal
10-(Dialkylaminoalkyl)-pyrido [3, 2-b][1, 4] benzothiazine (1-azaphenothiazine) and related compounds.
Yale HL and Sowinski F.
Journal of the American Chemical Society, 80(7), 1651-1654 (1958)
SUBSTITUTED 2,3-DIHYDRO-1,5-BENZOTHIAZEPIN-4(5H)-ONES AND 3,4-DIHYDRO-2-PHENYL-(2H)-1,6-BENZOTHIAZOCIN-5(6H)-ONES.
J KRAPCHO et al.
Journal of medicinal chemistry, 6, 544-546 (1963-09-01)
Efficient synthesis of heterophosphole-2-sulfides by solvent-free microwave reaction.
Seijas JA, et al.
Tetrahedron, 66(41), 8210-8213 (2010)

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