化驗
97%
折射率
n20/D 1.4226 (lit.)
密度
0.956 g/mL at 25 °C (lit.)
SMILES 字串
COC(CC(C)(C)O)OC
InChI
1S/C7H16O3/c1-7(2,8)5-6(9-3)10-4/h6,8H,5H2,1-4H3
InChI 密鑰
RLJXZLBECCIWMU-UHFFFAOYSA-N
一般說明
4,4-Dimethoxy-2-methyl-2-butanol is an organic building block.
應用
4,4-Dimethoxy-2-methyl-2-butanol may be used in the microwave-mediated synthesis of 2,2-dimethyl-2H-chromones. It may also be used in the preparation of alkyl substituted 3′R,4′R-di-O-(-)-camphanoyl-2′,2′-dimethyldihydropyrano[2,3-f]chromone (DCP) analogs.
儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 3
閃點（°F）
152.6 °F - closed cup
閃點（°C）
67 °C - closed cup
Ting Zhou et al.
Bioorganic & medicinal chemistry, 18(18), 6678-6689 (2010-08-24)
In a continued study, 23 3'R,4'R-di-O-(-)-camphanoyl-2',2'-dimethyldihydropyrano[2,3-f]chromone (DCP) derivatives (5-27) were synthesized, and screened for anti-HIV activity against both a non-drug-resistant NL4-3 strain and multiple reverse transcriptase (RT) inhibitor-resistant (RTMDR-1) strain, using 2-EDCP (4) and 2-MDCP (35) as controls. New DCP
Ting Zhou et al.
Tetrahedron letters, 51(33), 4382-4386 (2010-10-12)
A novel and efficient microwave-assisted one-pot reaction was developed to synthesize angular 2,2-dimethyl-2H-chromone containing compounds, which is the first and key step in the synthesis of potent DCK and DCP anti-HIV agents. The newly developed microwave synthesis conditions dramatically shortened
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