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Merck
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文件

47080

Sigma-Aldrich

5-氟吲哚

purum, ≥97.0% (GC)

同義詞:

NSC 88613

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About This Item

經驗公式(希爾表示法):
C8H6FN
CAS號碼:
分子量::
135.14
Beilstein:
112350
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:

等級

purum

化驗

≥97.0% (GC)

形狀

solid

mp

45-48 °C (lit.)
45-48 °C

儲存溫度

2-8°C

SMILES 字串

Fc1ccc2[nH]ccc2c1

InChI

1S/C8H6FN/c9-7-1-2-8-6(5-7)3-4-10-8/h1-5,10H

InChI 密鑰

ODFFPRGJZRXNHZ-UHFFFAOYSA-N

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應用

  • 用于制备 5-HT6 受体配体
  • 作为反应物,用于制备色氨酸双加氧酶抑制剂吡啶基-乙烯基-吲哚(一种潜在的抗癌免疫调节剂)
  • 用于制备抗肿瘤药物的反应物
  • 用于制备抗菌剂的反应物
  • 用于制备免疫抑制剂的反应物
  • 用于制备钠依赖性葡萄糖协同转运蛋白 2 (SGLT2) 抑制剂的反应物,用于治疗糖尿病高血糖症
  • 用于制备髓过氧化物酶抑制剂的反应物
  • 用于制备强效选择性 5-羟色胺再摄取抑制剂的反应物

取代透過

產品號碼
描述
訂價

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

儲存類別代碼

13 - Non Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

230.0 °F - closed cup

閃點(°C)

110 °C - closed cup

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


分析證明 (COA)

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Peter B Crowley et al.
Chemical communications (Cambridge, England), 48(86), 10681-10683 (2012-09-25)
Fluorine-containing amino acids are valuable probes for the biophysical characterization of proteins. Current methods for (19)F-labeled protein production involve time-consuming genetic manipulation, compromised expression systems and expensive reagents. We show that Escherichia coli BL21, the workhorse of protein production, can
Nicholas A Magnus et al.
Organic letters, 12(16), 3700-3703 (2010-08-14)
A practical synthesis of the glycogen synthase kinase-3 (GSK3) inhibitor bisarylmaleimide 1 has been accomplished employing Pictet-Spengler methodology to access the indole 7-position in preparing the benzodiazepine tricyclic fragment. A seven-step linear sequence that starts with commercially available 5-fluoroindole 7
Steffen P Graether et al.
Journal of magnetic resonance (San Diego, Calif. : 1997), 178(1), 65-71 (2005-10-04)
We show that it is feasible to use a minicoil for solid-state 19F 1H NMR experiments that has short pulse widths, good RF homogeneity, and excellent signal-to-noise for small samples while using low power amplifiers typical to liquid-state NMR. The
A L Palombella et al.
Plant physiology, 117(2), 455-464 (1998-06-25)
We report the isolation of a Chlamydomonas reinhardtii cDNA that encodes the beta-subunit of tryptophan synthase (TSB). This cDNA was cloned by functional complementation of a trp-operon-deleted strain of Escherichia coli. Hybridization analysis indicated that the gene exists in a
A J Barczak et al.
Genetics, 140(1), 303-313 (1995-05-01)
A study of the biochemical genetics of the Arabidopsis thaliana tryptophan synthase beta subunit was initiated by characterization of mutants resistant to the inhibitor 5-fluoroindole. Thirteen recessive mutations were recovered that are allelic to trp2-1, a mutation in the more

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