420964

(1S)-(+)-酮基蒎酸

99%

• 同義詞: (1S)-7,7-二甲基-2-氧代二环[2.2.1]庚烷-1-甲酸
• 經驗公式（希爾表示法）: C₁₀H₁₄O₃
• CAS號碼: 40724-67-2
• 分子量：: 182.22
• Beilstein: 4180005
• MDL號碼: MFCD00168053
• 分類程式碼代碼: 12352115
• PubChem物質ID: 24866367
• NACRES: NA.22

屬性

• 化驗: 99%
• 光學活性: [α]23/D +58°, c = 1 in chloroform
• mp: 237-239 °C (lit.)
• SMILES 字串: CC1(C)C2CCC1(C(O)=O)C(=O)C2
• InChI: 1S/C10H14O3/c1-9(2)6-3-4-10(9,8(12)13)7(11)5-6/h6H,3-5H2,1-2H3,(H,12,13)/t6-,10+/m1/s1
• InChI 密鑰: WDODWBQJVMBHCO-LDWIPMOCSA-N

描述

一般說明

(1S)-(+)-Ketopinic acid is a chiral ketone.

應用

用于制备新型手性噁唑烷酮辅助剂和酮基蒎酸衍生聚合物，该聚合物可用于胺的去外消旋化。合成纯手性 2,10-莰烷二醇的原料。用于生成手性席夫碱前体，以制备二乙基 (S)-α-氨基-α-烷基膦酸酯。

(1S)-(+)-Ketopinic acid may be used to prepare:

• Chiral phosphine-oxazoline ligands, which can used in asymmetric palladium-catalyzed Heck reaction of aryl or alkenyl triflates with cyclic alkenes.
• A chiral imino-phosphine ligand, which can be used in palladium-catalyzed asymmetric Diels–Alder reactions to prepare six-membered carbocycles.
• A chiral iminopyridine ligand, which can be used in copper-catalyzed Henry (nitro aldol) reaction between nitromethane and o-anisol to form the corresponding β-hydroxynitroalkane.

安全資訊

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H315,H319,H335
• 防範說明: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• 危險分類: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 標靶器官: Respiratory system
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 個人防護裝備: dust mask type N95 (US), Eyeshields, Gloves