393797

3-氨基-5-苯基吡唑

98%

• 經驗公式（希爾表示法）: C₉H₉N₃
• CAS號碼: 1572-10-7
• 分子量：: 159.19
• MDL號碼: MFCD00191749
• 分類程式碼代碼: 12352100
• PubChem物質ID: 24864542
• NACRES: NA.22

屬性

• 化驗: 98%
• mp: 124-127 °C (lit.)
• SMILES 字串: Nc1cc([nH]n1)-c2ccccc2
• InChI: 1S/C9H9N3/c10-9-6-8(11-12-9)7-4-2-1-3-5-7/h1-6H,(H3,10,11,12)
• InChI 密鑰: PWSZRRFDVPMZGM-UHFFFAOYSA-N

描述

一般說明

3-Amino-5-phenylpyrazole (3-phenyl-1H-pyrazol-5-amine), an amino pyrazole derivative, is an aza-heterocyclic amine. It has been reported to be synthesized by heating either 3-amino-4-bromo- or 3-amino-5-phenylisothiazole in the presence of anhydrous hydrazine. On reaction with ZnCl₂ it affords chlorido-tris(3-amino-5-phenyl-1Hpyrazole-N²)zinc (II) chloride.

應用

3-Amino-5-phenylpyrazole ((3-phenyl-1H-pyrazol-5-amine) may be used in the synthesis of the following:

• Urea derivatives by reaction with azido(6-(benzofuran-2-yl)-2-methylpyridin-3-yl) methanone.
• 2-Mercaptoacetamide analogs by treating with thioglycolic acid.
• 3-(Substituentpyrimidayl)-5,6-benzocoumarins by treating with 3-(2′-formyl-1′-chlorovinyl)-5,6-benzocoumarin.
• Substituted 2,7-diphenylpyrazolo[1,5-a]pyrimidine-5-carboxylic esters by reacting with substituted β-diketo esters.
• N-ethoxycarbonylthiourea derivative by reacting with ethoxycarbonyl isothiocyanate.
• Heterobiaryl pyrazolo[3,4-b]pyridines by reacting with indole-3-carboxaldehyde.

安全資訊

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H315,H319,H335
• 防範說明: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• 危險分類: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 標靶器官: Respiratory system
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: dust mask type N95 (US), Eyeshields, Gloves