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Merck
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文件

367001

Sigma-Aldrich

4,4′,4′′-三甲氧基三苯甲基氯

technical grade

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About This Item

線性公式:
(CH3OC6H4)3CCl
CAS號碼:
49757-42-8
分子量：:
368.85
EC號碼:
256-474-6
MDL號碼:
MFCD00008408
分類程式碼代碼:
12352101
PubChem物質ID:
24862380
NACRES:
NA.22

等級

technical grade

形狀

powder

mp

146-148 °C (lit.)

SMILES 字串

COc1ccc(cc1)C(Cl)(c2ccc(OC)cc2)c3ccc(OC)cc3

InChI

1S/C22H21ClO3/c1-24-19-10-4-16(5-11-19)22(23,17-6-12-20(25-2)13-7-17)18-8-14-21(26-3)15-9-18/h4-15H,1-3H3

InChI 密鑰

OBFCMKPFILBCSQ-UHFFFAOYSA-N

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相關類別

應用

4,4′,4″-Trimethoxytrityl chloride can be used:
  • In one of the key synthetic steps for the preparation of two phosphoramidite building blocks.
  • To prepare protein tagging molecule (3-[tris(4-methoxyphenyl)methylsulfanyl]propanoic acid by reacting with thioacetic acid.
  • To prepare C-2 amino trimethoxytrityl substituted nucleoside, which is a key intermediate for the synthesis of nucleoside based capping agent.

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves

分析證明 (COA)

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An effective method for the synthesis of the cap structure of eukaryotic messenger ribonucleic acids
Kamimura T, et al.
Tetrahedron Letters, 25(25), 2683-2686 (1984)
Novel reagents for terminal phosphorylation and thiophosphorylation of synthetic oligonucleotides
Guzaev AP and Manoharan M
Tetrahedron Letters, 42(29), 4769-4773 (2001)
Mass-tag enhanced immuno-laser desorption/ionization mass spectrometry for sensitive detection of intact protein antigens
Lorey M, et al.
Analytical Chemistry, 87(10), 5255-5262 (2015)

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