359343

氢化奎尼定

95%

• 同義詞: 双氢奎尼丁
• 經驗公式（希爾表示法）: C₂₀H₂₆N₂O₂
• CAS號碼: 1435-55-8
• 分子量：: 326.43
• Beilstein: 91441
• EC號碼: 215-862-5
• MDL號碼: MFCD00135599
• 分類程式碼代碼: 12352005
• PubChem物質ID: 24862070
• NACRES: NA.22

屬性

• 化驗: 95%
• 光學活性: [α]25/D +226°, c = 2 in ethanol
• mp: 169-170 °C (lit.)
• SMILES 字串: CC[C@H]1CN2CCC1CC2[C@@H](O)c3ccnc4ccc(OC)cc34
• InChI: 1S/C20H26N2O2/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18/h4-6,8,11,13-14,19-20,23H,3,7,9-10,12H2,1-2H3/t13-,14-,19+,20-/m0/s1
• InChI 密鑰: LJOQGZACKSYWCH-LHHVKLHASA-N
• 基因資訊: human ... CYP2D6(1565)

描述

一般說明

Hydroquinidine, a cinchona alkaloid, is a structural analog of quinidine. It shows antiarrhythmic effect.

應用

Hydroquinidine can be used as a chiral catalyst to prepare:

• Enantioselective axially chiral phosphamides by N-allylic alkylation reaction between Morita-Baylis-Hillamn (MBH) carbonate and phosphamides.
• Enantioselective α-amino phosphonates by hydrophosphonylation of N-aryl ketimines.
• Enantioselective α-hydrazino esters by α-hydrazination of 3-oxoindolines using azodicarboxylate via aza-Michael reaction.

安全資訊

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H302
• 防範說明: P264 - P270 - P301 + P312 - P501
• 危險分類: Acute Tox. 4 Oral
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: dust mask type N95 (US), Eyeshields, Gloves