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About This Item
經驗公式(希爾表示法):
C7H6ClNO2
CAS號碼:
分子量::
171.58
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22
化驗
97%
mp
162-164 °C (lit.)
SMILES 字串
Cc1ccc(C(O)=O)c(Cl)n1
InChI
1S/C7H6ClNO2/c1-4-2-3-5(7(10)11)6(8)9-4/h2-3H,1H3,(H,10,11)
InChI 密鑰
ACQXHCHKMFYDPM-UHFFFAOYSA-N
一般說明
2-Chloro-6-methylpyridine-3-carboxylic acid (2-Chloro-6-methylnicotinic acid) is a nicotinic acid derivative.
應用
2-Chloro-6-methylpyridine-3-carboxylic acid (2-Chloro-6-methylnicotinic acid) may be used in the synthesis of 6-methyl-2-thiophenoxynicotinic acid, required for the preparation of europium complex for staining the nucleolus of NIH 3T3, HeLa and HDF cells.
訊號詞
Warning
危險聲明
危險分類
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
Nicotinic acid derivatives. VI. Some transformations of 2-chloro-6-methylnicotinic acid.
P Nantka-Namirski et al.
Polish journal of pharmacology and pharmacy, 26(5), 545-548 (1974-07-01)
Junhua Yu et al.
Journal of the American Chemical Society, 128(7), 2294-2299 (2006-02-16)
A europium complex selectively staining the nucleolus of NIH 3T3, HeLa, and HDF cells is reported. This complex possesses not only the advantage of the long lifetime of europium emission (0.3 ms), but also a chromophore that allows excitation at
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