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Key Documents

281409

Sigma-Aldrich

2-碘苯酚

98%

同義詞:

1-碘-2-羟基苯, 2-羟基碘苯, 间碘苯酚

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About This Item

線性公式:
IC6H4OH
CAS號碼:
分子量::
220.01
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

品質等級

化驗

98%

形狀

solid

bp

186-187 °C/160 mmHg (lit.)

mp

37-40 °C (lit.)

密度

1.947 g/mL at 25 °C (lit.)

SMILES 字串

Oc1ccccc1I

InChI

1S/C6H5IO/c7-5-3-1-2-4-6(5)8/h1-4,8H

InChI 密鑰

KQDJTBPASNJQFQ-UHFFFAOYSA-N

一般說明

使用Mo(CO)6作为CO源并在微波辐射下2-碘苯酚与各种炔烃的钯催化羰基化快速环化反应已得到研究

應用

2-碘苯酚可用于合成:
  • 高对映体纯度的芳基2-苯并呋喃基和芳基2-吲哚甲醇
  • 3,3-二取代-2,3-二氢苯并呋喃

象形圖

Exclamation mark

訊號詞

Warning

危險分類

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

235.4 °F - closed cup

閃點(°C)

113 °C - closed cup

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


分析證明 (COA)

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R Koteshwar Rao et al.
Organic letters, 11(9), 1923-1926 (2009-04-04)
trans-3,4-Dihydro-2H-1,4-benzoxazine moieties can be synthesized by domino aziridine ring opening with o-iodophenols followed by the copper-catalyzed Goldberg coupling cyclization (intramolecular C(aryl)-N(amide) bond formation) with good to excellent yields.
Andrea Strube et al.
Water research, 43(20), 5216-5224 (2009-09-29)
The aim of the present study was to identify the compounds responsible for a characteristic medicinal off-odour in mineral water. 2-Dimensional high resolution gas chromatography-mass spectrometry analysis, in combination with olfactometry (HRGC-MS/O), led to the identification of 2-iodophenol and 2-iodo-4-methylphenol
K Suzuki et al.
Journal of biochemistry, 109(5), 791-797 (1991-05-01)
Salicylate hydroxylase [EC 1.14.13.1] from Pseudomonas putida catalyzes the hydroxylation of salicylate, and also o-aminophenol, o-nitrophenol, and o-halogenophenols, to catechol. The reactions with these o-substituted phenols comprise oxygenative deamination, denitration, and dehalogenation, respectively. The reaction stoichiometry, as to NADH oxidized
Synthesis of aryl 2-benzofuranyl and aryl 2-indolyl carbinols of high enantiomeric purity via palladium-catalyzed heteroannulation of chiral arylpropargylic alcohols.
Botta M, et al.
Tetrahedron Asymmetry, 7(5), 1263-1266 (1996)
Palladium-catalyzed cascade allylation/carbopalladation/cross coupling: a novel three-component reaction for the synthesis of 3, 3-disubstituted-2, 3-dihydrobenzofurans.
Szlosek-Pinaud, et al.
Tetrahedron Letters, 44(48), 8657-8659 (2003)

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