185175

1-苄基-3-吡咯烷酮

98%

• 經驗公式（希爾表示法）: C₁₁H₁₃NO
• CAS號碼: 775-16-6
• 分子量：: 175.23
• Beilstein: 1526217
• EC號碼: 212-274-0
• MDL號碼: MFCD00005342
• 分類程式碼代碼: 12352100
• PubChem物質ID: 24850673
• NACRES: NA.22

屬性

• 化驗: 98%
• 折射率: n20/D 1.539 (lit.)
• bp: 77 °C/0.01 mmHg (lit.)
• 密度: 1.091 g/mL at 25 °C (lit.)
• 儲存溫度: 2-8°C
• SMILES 字串: O=C1CCN(C1)Cc2ccccc2
• InChI: 1S/C11H13NO/c13-11-6-7-12(9-11)8-10-4-2-1-3-5-10/h1-5H,6-9H2
• InChI 密鑰: DHGMDHQNUNRMIN-UHFFFAOYSA-N

描述

一般說明

The equilibrium constant for the ketoreductase-catalyzed reduction reaction of 1-benzyl-3-pyrrolidinone has been measured in n-hexane. 1-Benzyl-3-pyrrolidinone on enzymatic asymmetric reduction yields enantiopure 1-benzyl-3-hydroxypyrrolidine, well known intermediate for various drugs.

應用

1-Benzyl-3-pyrrolidinone was used as starting reagent in the synthesis of vinyl triflate. It was used to prepare chiral, alkenyl sulfoximines leading to highly functionalized diazabicycles.

安全資訊

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H315,H319,H335
• 防範說明: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• 危險分類: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 標靶器官: Respiratory system
• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: 230.0 °F - closed cup
• 閃點（°C）: 110 °C - closed cup
• 個人防護裝備: Eyeshields, Gloves, type ABEK (EN14387) respirator filter