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重要文件

15719

Sigma-Aldrich

D -甘露醇

meets analytical specification of Ph. Eur., USP, FCC, E421, 98.0-101.5% (calc. to the dried substance, HPLC)

同義詞:

甘露糖醇

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About This Item

經驗公式(希爾表示法):
C6H14O6
CAS號碼:
分子量::
182.17
Beilstein:
1721898
EC號碼:
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:

化驗

98-102% (calc. to dried substance)
98.0-101.5% (calc. to the dried substance, HPLC)

光學活性

[α]20/D +23 to +25°, c = 8% in Na2B4O7
[α]25/D +137 to +145

品質

meets analytical specification of Ph. Eur., USP, FCC, E421

雜質

acidity or alcalinity, complies
reducing sugars, complies
related substances, in accordance (HPLC)
residual solvents, complies
sorbit (DC), complies
≤0.007% free acid (as CH3COOH)
≤0.5% water (Karl Fischer)

燃燒殘留物

≤0.1% (as SO4)

損耗

≤0.3% loss on drying, 105 °C, 4 h

pH值

5-7.5 (20 °C, 10%)

傅導性

20 μS/cm at 20 °C

mp

165-169 °C
167-170 °C (lit.)

負離子痕跡

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤100 mg/kg

正離子痕跡

As: ≤1 mg/kg
Cu: ≤10 mg/kg
Ni: ≤1 mg/kg
Zn: ≤10 mg/kg

適合性

complies for appearance of solution
passes test for identity (IR)

SMILES 字串

OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO

InChI

1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4-,5-,6-/m1/s1

InChI 密鑰

FBPFZTCFMRRESA-KVTDHHQDSA-N

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生化/生理作用

一种糖醇类甜味剂。 用于甜味抑制研究。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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分析證明 (COA)

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Heikki O Koskela et al.
Chest, 124(6), 2171-2177 (2003-12-11)
To compare a new bronchial provocation test, the mannitol challenge, with cold air and histamine challenges to demonstrate airway hyperresponsiveness (AHR) in patients with difficult-to-diagnose asthma. A prospective study. Thirty-seven consecutive patients with recently diagnosed, steroid-naive, mild, or atypical asthma
Maria Badal Tejedor et al.
International journal of pharmaceutics, 486(1-2), 315-323 (2015-04-07)
Tablets are the most convenient form for drug administration. However, despite the ease of manufacturing problems such as powder adhesion occur during the production process. This study presents surface and structural characterization of tablets formulated with commonly used excipients (microcrystalline
Diana Bilton et al.
Thorax, 69(12), 1073-1079 (2014-09-24)
Bronchiectasis is characterised by excessive production of mucus and pulmonary exacerbations. Inhaled osmotic agents may enhance mucociliary clearance, but few long-term clinical trials have been conducted. To determine the impact of inhaled mannitol on exacerbation rates in patients with non-cystic
Heikki O Koskela et al.
Chest, 125(6), 1985-1992 (2004-06-11)
To define whether coughing during mannitol challenge is a nonspecific side effect of this challenge or is associated with asthma. A prospective study. University hospital. Thirty-seven steroid-naive, asthmatic subjects and 10 healthy subjects. The participants completed a symptom questionnaire, recorded
Heikki O Koskela et al.
Chest, 124(4), 1341-1349 (2003-10-14)
To compare the sensitivity and validity of mannitol, histamine, and cold air challenges to demonstrate the effect of inhaled corticosteroids (ICS) in asthma. A prospective study. Seventeen patients with recently diagnosed, steroid-naive asthma who fulfilled the diagnostic criteria of Finnish

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