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122696

Sigma-Aldrich

DL-1,2-异亚丙基甘油

≥97.0%

同義詞:

(±)-2,2-二甲基-1,3-二氧戊环-4-甲醇, (±)-2,2-二甲基-4-羟甲基-1,3-二氧戊环, 1,2-Isopropylidene-rac-glycerol, 丙酮缩甘油

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About This Item

經驗公式(希爾表示法):
C6H12O3
CAS號碼:
分子量::
132.16
Beilstein:
104465
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

化驗

≥97.0%

形狀

liquid

折射率

n20/D 1.434 (lit.)

bp

188-189 °C (lit.)

溶解度

H2O: miscible
alcohol: miscible
diethyl ether: miscible
oil: miscible
petroleum ether: miscible

密度

1.063 g/mL at 25 °C (lit.)

SMILES 字串

CC1(C)OCC(CO)O1

InChI

1S/C6H12O3/c1-6(2)8-4-5(3-7)9-6/h5,7H,3-4H2,1-2H3

InChI 密鑰

RNVYQYLELCKWAN-UHFFFAOYSA-N

一般說明

DL-1,2-异亚丙基甘油在磷钨酸催化下发生有效的异亚丙基化脱保护反应

應用

以 DL-1,2-异亚丙基甘油为起始原料合成了郁金香酯衍生物

法律資訊

象形圖

Health hazardExclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Repr. 2

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

194.0 °F - closed cup

閃點(°C)

90 °C - closed cup

個人防護裝備

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


分析證明 (COA)

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Useful methods for the synthesis of isopropylidenes and their chemoselective cleavage.
Vanlaldinpuia K and Bez G.
Tetrahedron Letters, 52(29), 3759-3764 (2011)
Alvise Perosa et al.
Molecules (Basel, Switzerland), 21(2), 170-170 (2016-02-04)
The caprylic, lauric, palmitic and stearic esters of solketal and glycerol formal were synthesized with high selectivity and in good yields by a solvent-free acid catalyzed procedure. No acetal hydrolysis was observed, notwithstanding the acidic reaction conditions.
Thomas Mendgen et al.
Bioorganic & medicinal chemistry letters, 20(19), 5757-5762 (2010-08-24)
The enzyme MurA performs an essential step in peptidoglycan biosynthesis and is therefore a target for the discovery of novel antibacterial compounds. We report here the inhibition of MurA by natural products from tulips (tulipalines and tuliposides), and the structure-activity
Enzymatic synthesis of 2,3-O-isopropylidene-sn-glycerol, a chiral building block for platelet-activating factor.
H Suemune et al.
Chemical & pharmaceutical bulletin, 34(8), 3440-3444 (1986-08-01)
[Change in behavior of mice and rats under the effect of dimethyl-2,2 hydroxymethyl-4 dioxolanne-1,3 (glycerol acetonide)].
S L Cheav et al.
Annales pharmaceutiques francaises, 44(6), 487-494 (1986-01-01)

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