119725

4-哌啶苯乙酮

97%

• 同義詞: 1-[4-(1-Piperidinyl)]phenyl]ethanone
• 經驗公式（希爾表示法）: C₁₃H₁₇NO
• CAS號碼: 10342-85-5
• 分子量：: 203.28
• EC號碼: 233-746-2
• MDL號碼: MFCD00006481
• 分類程式碼代碼: 12352100
• PubChem物質ID: 24847298
• NACRES: NA.22

屬性

• 化驗: 97%
• mp: 85-87 °C (lit.)
• 官能基: ketone
• SMILES 字串: CC(=O)c1ccc(cc1)N2CCCCC2
• InChI: 1S/C13H17NO/c1-11(15)12-5-7-13(8-6-12)14-9-3-2-4-10-14/h5-8H,2-4,9-10H2,1H3
• InChI 密鑰: JCMZZYSPSGHBNM-UHFFFAOYSA-N

描述

一般說明

4′-Piperidinoacetophenone undergoes Claisen-Schmidt condensation with substituted benzaldehydes using NaOH-Al₂O₃ by microwave irradiation to give chalcones. It has antimycobacterial activity.

應用

4′-Piperidinoacetophenone was used as internal standard in the determination of pethidine, a narcotic analgesic drug in body fluids by gas chromatography-tandem mass spectrometry.

Pharmacological activity:

• Selective antimycobacterial activity
• Bronchodilator compound
• Modulation of flagellar motility in Chlamydomonas

安全資訊

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H315,H319,H335
• 防範說明: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• 危險分類: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 標靶器官: Respiratory system
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: dust mask type N95 (US), Eyeshields, Gloves