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Merck
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文件

103608

Sigma-Aldrich

3-硝基苯乙酸

99%

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About This Item

線性公式:
O2NC6H4CH2CO2H
CAS號碼:
分子量::
181.15
Beilstein:
2050088
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

化驗

99%

形狀

solid

mp

117-120 °C (lit.)

SMILES 字串

OC(=O)Cc1cccc(c1)[N+]([O-])=O

InChI

1S/C8H7NO4/c10-8(11)5-6-2-1-3-7(4-6)9(12)13/h1-4H,5H2,(H,10,11)

InChI 密鑰

WUKHOVCMWXMOOA-UHFFFAOYSA-N

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一般說明

3-Nitrophenylacetic acid is obtained by mild oxidation of 4-amino phenylacetic acid using potassium peroxymonosulfate as oxidizing agent in acetone.

應用

3-Nitrophenylacetic acid was used to study photodecarboxylation of nitrophenylacetate ions in aqueous solution. 3-Nitrophenylacetic acid was used in study to synthesize an azobenzene amino acid, having potent use as photo-inducible conformational switch in polypeptides.

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


分析證明 (COA)

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A mild oxidation of aromatic amines.
Webb KS and Seneviratne S.
Tetrahedron Letters, 36(14), 2377-2378 (1995)
Photodecarboxylation of nitrophenylacetate ions.
Margerum JD and Petrusis CT.
Journal of the American Chemical Society, 91(10), 2467-2472 (1969)
Andreas Aemissegger et al.
Nature protocols, 2(1), 161-167 (2007-04-03)
The synthesis of an azobenzene amino acid (aa) for use as a photo-inducible conformational switch in polypeptides is described. The compound can be easily incorporated into an aa sequence by solid-phase peptide synthesis using standard 9-fluorenylmethoxycarbonyl methods. A reversible conformational

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