ZAP70
zeta-chain (TCR) associated protein kinase 70kDa
同義詞:
SRK, STCD, STD, TZK, ZAP-70
物種:
Human ZAP70 (7535), Mouse Zap70 (22637), Rat Zap70 (301348), dog ZAP70 (100271860), domestic cat ZAP70 (101097059), chicken ZAP70 (420086), Zebrafish zap70 (553615), sheep ZAP70 (101112639), Domestic Rabbit ZAP70 (100342021), naked mole-rat Zap70 (101716577) ...更多
UniProtKB ID:
基因 ID:
- Human(7535) Summary: This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(22637) zeta-chain (TCR) associated protein kinase
- Rat(301348) zeta-chain (TCR) associated protein kinase 70
- dog(100271860) zeta-chain (TCR) associated protein kinase 70kDa
- domestic cat(101097059) zeta-chain (TCR) associated protein kinase 70kDa
- chicken(420086) zeta-chain (TCR) associated protein kinase 70kDa
- Zebrafish(553615) zeta-chain (TCR) associated protein kinase
- sheep(101112639) zeta-chain (TCR) associated protein kinase 70kDa
- Domestic Rabbit(100342021) zeta-chain (TCR) associated protein kinase 70kDa
- naked mole-rat(101716577) zeta-chain (TCR) associated protein kinase 70kDa
- domestic guinea pig(100713473) zeta-chain (TCR) associated protein kinase 70kDa
- cow(504509) zeta-chain (TCR) associated protein kinase 70kDa
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ELISA
產品編號
描述
物種
Antibodies
產品編號
描述
物種活性
應用
Anti-ZAP-70 Antibody, clone 2F3.2, clone 2F3.2, Upstate®, from mouse,
物種活性
human
應用
flow cytometry
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-ZAP-70 Antibody, clone 2F3.2, clone 2F3.2, Upstate®, from mouse,
物種活性
human
應用
flow cytometry
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-phospho-ZAP-70 (pTyr292) antibody produced in rabbit, affinity isolated antibody,
物種活性
human, mouse, rat
應用
ELISA
western blot
western blot
Anti-phospho-ZAP70 (pTyr319) antibody produced in rabbit, affinity isolated antibody,
物種活性
human, mouse, rat
應用
immunofluorescence
western blot
western blot
Monoclonal Anti-ZAP-70 antibody produced in mouse, ~1.5 mg/mL, clone 1E7.2, purified immunoglobulin, buffered aqueous solution,
物種活性
human, mouse
應用
ELISA
flow cytometry
immunocytochemistry
immunoprecipitation (IP)
microarray
western blot
flow cytometry
immunocytochemistry
immunoprecipitation (IP)
microarray
western blot
Proteins
產品編號
描述
物種
ZAP-70 Tyrosine Kinase human, ≥90% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells (Histidine tagged), buffered aqueous glycerol solution, ≥150 U/mg,
物種
human
ZAP-70 Protein, active, 20 µg, Active, recombinant, human, full length ZAP-70 containing a C-terminal His6 tag, for use in Kinase Assays.,
物種
human