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Merck

TRPV1

transient receptor potential cation channel, subfamily V, member 1

同義詞:
VR1
物種:
UniProtKB ID:
基因 ID:
  • Human(7442) Summary: Capsaicin, the main pungent ingredient in hot chili peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. The protein encoded by this gene is a receptor for capsaicin and is a non-selective cation channel that is structurally related to members of the TRP family of ion channels. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo. Four transcript variants encoding the same protein, but with different 5' UTR sequence, have been described for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(193034) transient receptor potential cation channel, subfamily V, member 1
  • Rat(83810) transient receptor potential cation channel, subfamily V, member 1
  • domestic cat(101093406) transient receptor potential cation channel, subfamily V, member 1
  • chicken(395259) transient receptor potential cation channel, subfamily V, member 1
  • naked mole-rat(101720480) transient receptor potential cation channel, subfamily V, member 1
  • Domestic Rabbit(100008926) transient receptor potential cation channel, subfamily V, member 1
  • domestic cat(100303454) transient receptor potential cation channel, subfamily V, member 1
  • Zebrafish(561195) transient receptor potential cation channel, subfamily V, member 1
  • cow(539074) transient receptor potential cation channel, subfamily V, member 1
  • domestic guinea pig(100135466) transient receptor potential cation channel, subfamily V, member 1
  • Horse(100034158) transient receptor potential cation channel, subfamily V, member 1
  • sheep(101110158) transient receptor potential cation channel, subfamily V, member 1
  • dog(445457) transient receptor potential cation channel, subfamily V, member 1

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Small Molecule - Agonist

產品編號
描述
物種
二氢辣椒碱, from Capsicum sp., ≥85%,
物種
rat, human
N-香草基壬酰胺, ≥97%, powder,
物種
rat
油酰单乙醇胺, ~98% (TLC),
物種
human, mouse, rat

Small Molecule - Antagonist

產品編號
描述
物種
SB-366791, ≥98% (HPLC), powder,
物種
human
6-Iodonordihydrocapsaicin, ≥98% (HPLC), solid,
物種
human
辣椒平, ≥98% (HPLC), solid,
物種
human, rat
辣椒素, ≥95%, from Capsicum sp.,
物種
rat, human
辣椒素, natural,
物種
rat, human

Antibodies

產品編號
描述
物種活性
應用
抗辣椒素受体抗体,CT, serum, Chemicon®,
物種活性
rat
應用
immunohistochemistry
抗-TRPV1 兔抗, affinity isolated antibody,
物種活性
human
應用
ELISA
western blot
单克隆抗-TRPV1 小鼠抗, clone 1F5, purified immunoglobulin, buffered aqueous solution,
物種活性
human
應用
ELISA
western blot
Monoclonal Anti-TRPV1 antibody produced in mouse, clone 1A8, purified immunoglobulin, buffered aqueous solution,
物種活性
human
應用
ELISA
western blot
Anti-Vanilloid Receptor-1 antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
物種活性
rat
應用
microarray
western blot

Small Molecule - Inhibitor

產品編號
描述
物種
Olvanil, powder,
物種
human
辣椒素, ≥95%, from Capsicum sp.,
物種
rat, human
对乙酰氨基酚, Pharmaceutical Secondary Standard; Certified Reference Material,
物種
human
对乙酰氨基酚, United States Pharmacopeia (USP) Reference Standard,
物種
human
对乙酰氨基酚, BioXtra, ≥99.0%,
物種
human

Small Molecule - Mixed Agonist/Antagonist

產品編號
描述
物種
N-香草基壬酰胺, ≥97%, powder,
物種
rat
辣椒平, ≥98% (HPLC), solid,
物種
human, rat

Small Molecule - Opener

產品編號
描述
物種
辣椒素, analytical standard,
物種
human
辣椒素, United States Pharmacopeia (USP) Reference Standard,
物種
human
辣椒碱, Pharmaceutical Secondary Standard; Certified Reference Material,
物種
human
辣椒素, European Pharmacopoeia (EP) Reference Standard,
物種
human
对乙酰氨基酚, Pharmaceutical Secondary Standard; Certified Reference Material,
物種
human

Proteins

產品編號
描述
物種
Capsaicin Receptor Control Peptide for AB5889, ,
物種
rat