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Merck

PRKCB

protein kinase C, beta

同義詞:
PKC-beta, PKCB, PRKCB1, PRKCB2
物種:
Human PRKCB (5579), Mouse Prkcb (18751), Rat Prkcb (25023), Domestic Rabbit PRKCB (100037719), sheep PRKCB (101118410), naked mole-rat Prkcb (101722702), domestic cat PRKCB (101088970), chicken PRKCB (416567), dog PRKCB (489968), cow PRKCB (282325)
UniProtKB ID:
P05771, C5IFJ8, D3DWF5, O43744, P05127, Q15138, Q93060, Q9UE49
基因 ID:
  • Human(5579) Summary: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
  • Mouse(18751) protein kinase C, beta
  • Rat(25023) protein kinase C, beta
  • Domestic Rabbit(100037719) protein kinase C, beta
  • sheep(101118410) protein kinase C, beta
  • naked mole-rat(101722702) protein kinase C, beta
  • domestic cat(101088970) protein kinase C, beta
  • chicken(416567) protein kinase C, beta
  • dog(489968) protein kinase C, beta
  • cow(282325) protein kinase C, beta

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Small Molecule - Agonist

產品編號
描述
物種
O1008
油酸, ≥99% (GC),
物種
human

Antibodies

產品編號
描述
物種活性
應用
SAB1306182
ANTI-PKC BETA2(C-TERMINAL) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
物種活性
human, mouse, primate, rat
應用
immunohistochemistry
western blot
P5704
单克隆抗 蛋白激酶 C (PKC) 小鼠抗, clone MC5, ascites fluid,
物種活性
bovine, human, mouse, rat
應用
immunohistochemistry
immunoprecipitation (IP)
microarray
western blot
SAB4504099
Anti-phospho-PKC-pan (pThr497) antibody produced in rabbit, affinity isolated antibody,
物種活性
human, mouse, rat
應用
ELISA
immunofluorescence
immunohistochemistry
western blot

Small Molecule - Inhibitor

產品編號
描述
物種
H5257
Hispidin, solid, ≥98% (HPLC),
物種
human
I7016
H-7 dihydrochloride, ≥98% (HPLC),
物種
human
T9262
他莫昔芬 柠檬酸盐, ≥99%,
物種
human
O1008
油酸, ≥99% (GC),
物種
human
U6508
UCN-01, ≥97% (HPLC), powder,
物種
human

Proteins

產品編號
描述
物種
P3287
Protein kinase CβII isozyme human, >85% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells, buffered aqueous glycerol solution,
物種
human