推薦產品
生物源
synthetic (organic)
化驗
≥98% (HPLC)
形狀
solid
儲存條件
protect from light
顏色
yellow to brown
mp
237.5-238.5 °C
溶解度
DMSO: >10 mg/mL
儲存溫度
−20°C
SMILES 字串
OC1=CC(/C=C/C(O2)=CC(O)=CC2=O)=CC=C1O
InChI
1S/C13H10O5/c14-9-6-10(18-13(17)7-9)3-1-8-2-4-11(15)12(16)5-8/h1-7,14-16H/b3-1+
InChI 密鑰
SGJNQVTUYXCBKH-HNQUOIGGSA-N
基因資訊
human ... PRKACB(5567) , PRKAR2B(5577) , PRKCB(5579)
一般說明
Hispidin is a phenolic compound, that is obtained from a medicinal mushroom, Phellinus linteus.
生化/生理作用
Hispidin exhibits robust antioxidant, anticancer and antidiabetic properties. It has the ability to guard against peroxynitrite-mediated cytotoxicity, DNA damage and the development of hydroxyl radicals.
Potent inhibitor of protein kinase Cβ, cytotoxic for cancer cells.
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
No data available
閃點(°C)
No data available
個人防護裝備
Eyeshields, Gloves, type N95 (US)
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。
International journal of molecular sciences, 22(3) (2021-02-13)
KV1.5 channel function is modified by different regulatory subunits. KVβ1.3 subunits assemble with KV1.5 channels and induce a fast and incomplete inactivation. Inhibition of PKC abolishes the KVβ1.3-induced fast inactivation, decreases the amplitude of the current KV1.5-KVβ1.3 and modifies their
Chemico-biological interactions, 199(3), 137-142 (2012-07-24)
Oxidative stress plays an important role in the progression of many chronic diseases including cardiovascular diseases, diabetes, cancer and neurodegenerative disorders. One such mediator of oxidative stress is peroxynitrite, which is highly toxic to cultured neurons and astrocytes, and has
Fungal Light Emitter: Understanding Its Chemical Nature and pH-Dependent Emission in Water Solution.
The Journal of organic chemistry, 85(8), 5503-5510 (2020-03-24)
Fungal bioluminescence is a fascinating natural process, standing out for the continuous conversion of chemical energy into light. The structure of fungal oxyluciferin (light emitter) was proposed in 2017, being different and more complex than other oxyluciferins. The complexity of
Journal of natural products, 75(10), 1683-1689 (2012-10-03)
In this study the protective effects of davallialactone (1), isolated from Inonotus xeranticus, have been examined against carbon tetrachloride (CCl₄-induced acute liver injury. Mice received subcutaneous injection of 1 (2.5, 5, and 10 mg/kg) for three days before CCl₄ injection
The Journal of investigative dermatology, 126(2), 460-467 (2005-12-24)
Activation of protein kinase C (PKC) induces phenotypic changes in the morphology of microvascular endothelial cells that affect major functions of the microvasculature. These functions include the first stages of sprouting in angiogenesis, cell migration following wounding, and vascular permeability.
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