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Merck

NPHS2

nephrosis 2, idiopathic, steroid-resistant (podocin)

同義詞:
PDCN, SRN1
物種:
UniProtKB ID:
基因 ID:
  • Human(7827) Summary: This gene encodes the glomerular protein podocin which plays a role in the regulation of glomerular permeability, and acts as a linker between the plasma membrane and the cytoskeleton. Defects in this gene are the cause of autosomal recessive steroid-resistant nephrotic syndrome (SRN). SRN is characterized by onset between three months and five years, resistance to steroid therapy and rapid progression to end-stage renal disease. An alternative splice variant has been described but its full length sequence has not been determined. [provided by RefSeq, Jul 2008]
  • Mouse(170484) nephrosis 2, podocin
  • Rat(170672) nephrosis 2, idiopathic, steroid-resistant
  • Zebrafish(557914) nephrosis 2, idiopathic, steroid-resistant (podocin)
  • chicken(424422) nephrosis 2, idiopathic, steroid-resistant (podocin)
  • dog(490323) nephrosis 2, idiopathic, steroid-resistant (podocin)
  • sheep(101121618) nephrosis 2, idiopathic, steroid-resistant (podocin)
  • cow(537633) nephrosis 2, idiopathic, steroid-resistant (podocin)
  • domestic guinea pig(100716190) nephrosis 2, idiopathic, steroid-resistant (podocin)
  • naked mole-rat(101704471) nephrosis 2, idiopathic, steroid-resistant (podocin)
  • domestic cat(101084927) nephrosis 2, idiopathic, steroid-resistant (podocin)

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Antibodies

產品編號
描述
物種活性
應用
抗- Podocin,小鼠单克隆抗体, clone PD-65, purified from hybridoma cell culture,
物種活性
bovine, human, mouse, rat
應用
immunofluorescence
western blot
Anti-NPHS2 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
物種活性
human
應用
western blot
抗 膜蛋白 兔抗, affinity isolated antibody, buffered aqueous solution,
物種活性
human, mouse, rat
應用
immunofluorescence
western blot