跳轉至內容
Merck

KCNQ4

potassium voltage-gated channel, KQT-like subfamily, member 4

同義詞:
DFNA2, DFNA2A, KV7.4
物種:
UniProtKB ID:
基因 ID:
  • Human(9132) Summary: The protein encoded by this gene forms a potassium channel that is thought to play a critical role in the regulation of neuronal excitability, particularly in sensory cells of the cochlea. The current generated by this channel is inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. The encoded protein can form a homomultimeric potassium channel or possibly a heteromultimeric channel in association with the protein encoded by the KCNQ3 gene. Defects in this gene are a cause of nonsyndromic sensorineural deafness type 2 (DFNA2), an autosomal dominant form of progressive hearing loss. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(60613) potassium voltage-gated channel, subfamily Q, member 4
  • Rat(298496) potassium voltage-gated channel, KQT-like subfamily, member 4
  • chicken(419643) potassium voltage-gated channel, KQT-like subfamily, member 4
  • naked mole-rat(101714294) potassium voltage-gated channel, KQT-like subfamily, member 4
  • domestic guinea pig(100716024) potassium voltage-gated channel, KQT-like subfamily, member 4
  • sheep(101122655) potassium voltage-gated channel, KQT-like subfamily, member 4
  • Domestic Rabbit(100358271) potassium voltage-gated channel, KQT-like subfamily, member 4
  • domestic cat(101091641) potassium voltage-gated channel, KQT-like subfamily, member 4
  • Horse(100067963) potassium voltage-gated channel, KQT-like subfamily, member 4
  • cow(528741) potassium voltage-gated channel, KQT-like subfamily, member 4
  • dog(482451) potassium voltage-gated channel, KQT-like subfamily, member 4

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Activator

產品編號
描述
物種
BMS 204352, ≥98% (HPLC),
物種
human

Small Molecule - Blocker

產品編號
描述
物種
瑞替加滨, ≥98% (HPLC),
物種
human
瑞替加滨, analytical standard,
物種
human
Retigabine solution, 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®,
物種
human
盐酸胍 盐酸盐, for molecular biology, ≥99%,
物種
human
盐酸胍 盐酸盐, ≥98%,
物種
human

Small Molecule - Inhibitor

產品編號
描述
物種
N -乙基马来酰亚胺, crystalline, ≥98% (HPLC),
物種
human