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Merck

GP1BA

glycoprotein Ib (platelet), alpha polypeptide

同義詞:
BDPLT1, BDPLT3, BSS, CD42B, CD42b-alpha, DBPLT3, GP1B, GPIbA, VWDP
物種:
UniProtKB ID:
基因 ID:
  • Human(2811) Summary: Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that is linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Several polymorphisms and mutations have been described in this gene, some of which are the cause of Bernard-Soulier syndromes and platelet-type von Willebrand disease. [provided by RefSeq, Mar 2010]
  • Mouse(14723) glycoprotein 1b, alpha polypeptide
  • Rat(691992) glycoprotein Ib (platelet), alpha polypeptide
  • chicken(420059) glycoprotein Ib (platelet), alpha polypeptide
  • naked mole-rat(101717127) glycoprotein Ib (platelet), alpha polypeptide
  • domestic guinea pig(100717535) glycoprotein Ib (platelet), alpha polypeptide
  • sheep(101109891) glycoprotein Ib (platelet), alpha polypeptide
  • cow(504977) glycoprotein Ib (platelet), alpha polypeptide
  • domestic cat(101092307) glycoprotein Ib (platelet), alpha polypeptide
  • dog(403638) glycoprotein Ib (platelet), alpha polypeptide

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Antibodies

產品編號
描述
物種活性
應用
Monoclonal Anti-CD42b antibody produced in mouse, clone HIP1, purified immunoglobulin, buffered aqueous solution,
物種活性
human, nonhuman primates
應用
flow cytometry
Monoclonal Anti-GP1BA antibody produced in mouse, clone 2E5, purified immunoglobulin, buffered aqueous solution,
物種活性
human
應用
ELISA
Milli-Mark® Anti-CD42b-PE Antibody, clone AN51, clone AN51, Milli-Mark®, from mouse,
物種活性
human
應用
flow cytometry
Anti-CD42B antibody, Rabbit monoclonal, recombinant, expressed in proprietary host, clone SP202, affinity isolated antibody,
物種活性
human, mouse
應用
immunohistochemistry
Anti-GP1BA antibody produced in rabbit, affinity isolated antibody,
物種活性
human
應用
western blot