FCMAB196P

Milli-Mark^® Anti-CD42b-PE Antibody, clone AN51

clone AN51, Milli-Mark^®, from mouse

• 同義詞: Platelet glycoprotein Ib alpha chain, Glycoprotein Ibalpha, GP-Ib alpha, GPIb-alpha, GPIbA, Antigen CD42b-alpha
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.44

屬性

• 生物源: mouse
• 品質等級: 100
• 共軛: PE
• 抗體表格: purified immunoglobulin
• 抗體產品種類: primary antibodies
• 無性繁殖: AN51, monoclonal
• 物種活性: human
• 製造商／商標名: Milli-Mark^®
• 技術: flow cytometry: suitable
• 同型: IgG2aκ
• NCBI登錄號: NP_000164
• UniProt登錄號: P07359
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified
• 基因資訊: human ... GP1BA(2811)

描述

一般說明

CD42b is a 145 kDa protein, which together with CD42c forma a 160 kDa heterodimer composed of an alpha-chain and a beta-chain, respectively. The subunits are linked together by a disulphide bond. CD42b and CD42c forms a non-covalent complex together with CD42a and CD42d in the platelet plasma membrane. The CD42 complex serves as a receptor for von Willebrand factor and thrombin and mediates adhesion of platelets to subendothelial matrices (exposed upon damage to the endothelium) at high shear rates. The binding sites for von Willebrand factor and thrombin lies on CD42b (de Haas, 2002). CD42 is expressed on megakarytocytes and platelets (McMichael, 1981).

特異性

Antibody recognizes Human CD42b antigen.

免疫原

Mixture of human platelets and lymphocytes.

應用

Research Category
Inflammation & Immunology

Research Sub Category
Immunoglobulins & Immunology

This Milli-Mark Anti-CD42b-PE Antibody, clone AN51 is validated for use in FC for the detection of CD42b.

品質

Evaluated by flow cytometry using human lymphocytes

標靶描述

145 kDa (de Haas, 2002)

外觀

Protein A purified

Purified Mouse monoclonal IgG2a conjugated to PE in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2.

儲存和穩定性

Maintain refrigerated at 2-8°C protected from light in undiluted aliquots for up to 6 months from date of receipt.

分析報告

Control
Human Lymphocytes

法律資訊

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable