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Merck

ESR2

estrogen receptor 2 (ER beta)

同義詞:
ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2
物種:
UniProtKB ID:
基因 ID:
  • Human(2100) Summary: This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized. [provided by RefSeq, Jul 2008]
  • Mouse(13983) estrogen receptor 2 (beta)
  • Rat(25149) estrogen receptor 2 (ER beta)
  • dog(403639) estrogen receptor 2 (ER beta)
  • chicken(395575) estrogen receptor 2 (ER beta)
  • domestic guinea pig(100731304) estrogen receptor 2 (ER beta)
  • Domestic Rabbit(100346748) estrogen receptor 2 (ER beta)
  • domestic cat(101086317) estrogen receptor 2 (ER beta)
  • Horse(100033964) estrogen receptor 2 (ER beta)
  • cow(281146) estrogen receptor 2 (ER beta)
  • Goat(100860823) estrogen receptor 2 (ER beta)
  • sheep(443066) estrogen receptor 2 (ER beta)

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Small Molecule - Activator

產品編號
描述
物種
β-烟酰胺腺嘌呤二核苷酸 钠盐, ,
物種
human
β-烟酰胺腺嘌呤二核苷酸 水合物, ≥95% (HPLC),
物種
human
β-烟酰胺腺嘌呤二核苷酸, pkg of 10 mg (per vial),
物種
human
β-烟酰胺腺嘌呤二核苷酸 水合物, ≥96.5% (HPLC), ≥96.5% (spectrophotometric assay), from yeast,
物種
human
β-烟酰胺腺嘌呤二核苷酸, pkg of 50 mg (per vial),
物種
human

Small Molecule - Agonist

產品編號
描述
物種
ERB-041, ≥98% (HPLC),
物種
human
17α-Ethynylestradiol 3-cyclopentyl ether, ,
物種
human
4-{1-Ethyl-2-[4-(phosphonooxy)phenyl]-1-butenyl}phenyl dihydrogen phosphate, ,
物種
human
雌素酮, ≥99%,
物種
human, mouse, rat

Small Molecule - Allosteric Modulator

產品編號
描述
物種
Raloxifene hydrochloride, United States Pharmacopeia (USP) Reference Standard,
物種
human
Raloxifene hydrochloride, solid,
物種
human
Estramustine sodium phosphate, ,
物種
human
Raloxifene Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
物種
human
Toremifene citrate salt, ≥98% (HPLC),
物種
human

Small Molecule - Antagonist

產品編號
描述
物種
氟维司群, >98% (HPLC),
物種
human
2-甲氧基雌二醇, powder,
物種
human
氟维司群, United States Pharmacopeia (USP) Reference Standard,
物種
human
氟维司群, European Pharmacopoeia (EP) Reference Standard,
物種
human
氟维司群, European Pharmacopoeia (EP) Reference Standard,
物種
human

Antibodies

產品編號
描述
物種活性
應用
抗雌激素受体β抗体,克隆68-4,兔单克隆, clone 68-4, Upstate®, from rabbit,
物種活性
human
應用
immunoprecipitation (IP)
western blot
单克隆抗 ESR2 小鼠抗, ,
物種活性
human, monkey, mouse
應用
ChIP
dot blot

flow cytometry

immunocytochemistry

immunofluorescence

immunohistochemistry

western blot
抗-雌激素受体-β 兔抗, affinity isolated antibody,
物種活性
human, mouse, rat
應用
ELISA
immunofluorescence

western blot
Anti-Estrogen Receptor β Antibody, clone 9.88, clone 9.88, from mouse,
物種活性
human, mouse, rat
應用
immunoprecipitation (IP)
western blot
Anti-ESR2 antibody produced in rabbit, affinity isolated antibody,
物種活性
human
應用
western blot

Small Molecule - Mixed Agonist/Antagonist

產品編號
描述
物種
α-雌二醇, powder, ≥98% (TLC),
物種
human, rat
雌二醇, meets USP testing specifications,
物種
human, mouse, rat
β-雌二醇, BioReagent, powder, suitable for cell culture,
物種
human, mouse, rat
β-雌二醇, ≥98%,
物種
human, mouse, rat
β-雌二醇, powder, γ-irradiated, suitable for cell culture,
物種
human, mouse, rat