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Merck

CDKN2D

cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)

同義詞:
INK4D, p19, p19-INK4D
物種:
UniProtKB ID:
基因 ID:
  • Human(1032) Summary: The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to form a stable complex with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. The abundance of the transcript of this gene was found to oscillate in a cell-cycle dependent manner with the lowest expression at mid G1 and a maximal expression during S phase. The negative regulation of the cell cycle involved in this protein was shown to participate in repressing neuronal proliferation, as well as spermatogenesis. Two alternatively spliced variants of this gene, which encode an identical protein, have been reported. [provided by RefSeq, Jul 2008]
  • Mouse(12581) cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
  • Rat(494444) similar to cyclin-dependent kinase inhibitor 2D
  • domestic guinea pig(100717134) cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
  • dog(611216) cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
  • naked mole-rat(101720531) cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
  • domestic cat(101091765) cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
  • cow(510244) cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
  • sheep(101118528) cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)

Custom & Knockdown Gene Products

Antibodies

產品編號
描述
物種活性
應用
Monoclonal Anti-CDKN2D antibody produced in mouse, clone 2E10, purified immunoglobulin, buffered aqueous solution,
物種活性
human
應用
ELISA
immunoprecipitation (IP)

western blot

Small Molecule - Inhibitor

產品編號
描述
物種
核抑制剂, ≥98% (TLC),
物種
human, mouse, rat
奥罗莫星, ≥98% (HPLC),
物種
human, rat