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Merck

ADRA2C

adrenoceptor alpha 2C

同義詞:
ADRA2L2, ADRA2RL2, ADRARL2, ALPHA2CAR
物種:
UniProtKB ID:
基因 ID:
  • Human(152) Summary: Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. The mouse studies revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes the alpha2C subtype, which contains no introns in either its coding or untranslated sequences. [provided by RefSeq, Jul 2008]
  • Mouse(11553) adrenergic receptor, alpha 2c
  • Rat(24175) adrenoceptor alpha 2C
  • domestic guinea pig(100135477) adrenergic receptor, alpha 2c
  • domestic guinea pig(101787589) adrenoceptor alpha 2C
  • cow(101902575) adrenoceptor alpha 2C
  • cow(407139) alpha-2C adrenergic receptor
  • sheep(100170319) adrenoceptor alpha 2C
  • Zebrafish(266752) adrenergic, alpha-2C-, receptor
  • chicken(428799) adrenergic, alpha-2C-, receptor
  • dog(488793) adrenoceptor alpha 2C
  • domestic cat(101087990) adrenoceptor alpha 2C
  • domestic cat(100529244) adrenoceptor alpha 2C

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Small Molecule - Agonist

產品編號
描述
物種
可乐定 盐酸盐, solid,
物種
human
甲苯噻嗪 盐酸盐, ≥99.0% (HPLC),
物種
human
Guanfacine hydrochloride, United States Pharmacopeia (USP) Reference Standard,
物種
human
Guanfacine hydrochloride, ≥98% (HPLC),
物種
human
胍那苄 乙酸盐, powder,
物種
human

Small Molecule - Antagonist

產品編號
描述
物種
育亨宾 盐酸盐, ≥98% (HPLC), powder,
物種
human
Idazoxan hydrochloride, ,
物種
human
RX 821002 hydrochloride, solid, ≥98% (HPLC),
物種
human
UK 14,304, ,
物種
human
米氮平 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
物種
human

Antibodies

產品編號
描述
物種活性
應用
Anti-Adrenergic Receptor α-2C antibody produced in rabbit, affinity isolated antibody,
物種活性
human, mouse, rat
應用
ELISA
western blot
Anti-α2C Adrenergic Receptor antibody produced in rabbit, ~1 mg/mL, affinity isolated antibody, buffered aqueous solution,
物種活性
human, mouse, rat
應用
immunohistochemistry
western blot

Small Molecule - Blocker

產品編號
描述
物種
米赛林 盐酸盐, ,
物種
human
胍丁胺 硫酸盐, ≥97%, powder,
物種
human

Small Molecule - Mixed Agonist/Antagonist

產品編號
描述
物種
UK 14,304, ,
物種
human
(−)-去甲肾上腺素, ≥98%, crystalline,
物種
human, rat
氟哌啶醇, powder,
物種
human, rat
氯氮平标准液, ,
物種
human, rat