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Key Documents

SAB1102826

Sigma-Aldrich

Anti-TM4SF19 (146-160) antibody produced in rabbit

IgG fraction of antiserum

Synonym(s):

Anti-OCTM4, Anti-Transmembrane 4 L six family member 19

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
Pricing and availability is not currently available.

biological source

rabbit

conjugate

unconjugated

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen ~22 kDa

species reactivity

human

technique(s)

western blot: 1:500-1:2,000

UniProt accession no.

Q96DZ7

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... TM4SF19(116211)

General description

Transmembrane 4 L six family member 19 (TM4SF19) or osteoclast maturation-associated gene 4 protein (OCTM4) belongs to the transmembrane 4 L six superfamily. TM4SF19 gene is mapped to human chromosome 3q29.

Immunogen

synthetic peptide corresponding to amino acids 146-160 of human TM4SF19

Biochem/physiol Actions

Transmembrane 4 L six family member 19 (TM4SF19) expression is detected in the chronic heart disease samples especially in the cells, sera and tissues. It may contribute to atherosclerosis progression and may serve as a potential marker for screening atherosclerosis.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
011M2723

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Adela Chirita Emandi et al.
Frontiers in pediatrics, 7, 270-270 (2019-07-25)
3q29 deletion syndrome is a rare disorder, causing a complex phenotype. Clinical features are variable and relatively non-specific. Our report aims to present an atypical, de novo deletion in chromosome band 3q29 in a preschool boy, first child of healthy
Li Ding et al.
Biochemical and biophysical research communications, 533(4), 1204-1211 (2020-10-17)
Atherosclerosis is a chronic vascular inflammatory disease that initially starts from an arterial intima lesion and endothelial barrier dysfunction. The purpose of this study was to investigate the role of TM4SF19, a recently identified member of the transmembrane 4L six
Yuji Kubota et al.
Nature communications, 13(1), 4063-4063 (2022-07-14)
Point-mutations of MEK1, a central component of ERK signaling, are present in cancer and RASopathies, but their precise biological effects remain obscure. Here, we report a mutant MEK1 structure that uncovers the mechanisms underlying abnormal activities of cancer- and RASopathy-associated

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