This product is used in research applications as a delivery vehicle for fat-soluble compounds including steroidal hormones and toxins. That said, it is not QC tested in an injectable format on animals or humans (though many researchers do use research-grade products with animals) so its use in that manner cannot be guaranteed. The literature articles on the product page do not mention its use in slow-release galenic products, so this is something the end user would need to determine.
S3547
Sesame oil
Sesame oil
Antioxidant, delivery vehicle for fat-soluble compounds
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About This Item
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biological source
Sesamum indicum (sesame)
Quality Level
form
liquid
density
0.92 g/mL at 25 °C
functional group
oleic acid
lipid type
oils
shipped in
ambient
storage temp.
room temp
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General description
Sesame oil may be used in the production of biodiesel and may serve as a viable alternative for the diesel fuel.[1] It acts as an antioxidant having neuroprotective activity on brain hippocampus of rat in focal cerebral ischemia, when given as a dietary supplement.[2] Consumption of sesame oil has a beneficial effect on blood glucose, glycosylated hemoglobin, lipid peroxidation, and antioxidant levels in diabetic rats.[3]
Application
Sesame oil is suitable:
- for dissolving free testosterone[4]
- for the preparation of tamoxifen i.p. injection[5]
- for dissolving aromatizable androgen testosterone and non-aromatizable androgen 5α-dihydrotestosterone[6]
- as a delivery vehicle for the injection of estradiol benzoate[7]
- for dissolving progesterone and estradiol-17β[8]
- for dissolving semisynthetic form of acetyl-11-keto-β-boswellic acid[9]
Used in research applications as delivery vehicle for fat-soluble compounds including steroidal hormones and toxins. Sesame oil has antioxidant properties and was shown to protect against lipopolysaccharide (LPS)-stimulated oxidative stress in animal models.
Storage Class Code
10 - Combustible liquids
WGK
awg
Flash Point(F)
491.0 °F
Flash Point(C)
255 °C
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Saif Ahmad et al.
Life sciences, 79(20), 1921-1928 (2006-07-11)
Oxidative stress may be regarded as an imbalance between free radical production and opposing antioxidant defenses. Free radical oxidative stress is implicated in rat cerebral ischemia and naturaceutical antioxidants are dietary supplements that have been reported to have neuroprotective activity.
Abdurrahman Saydut et al.
Bioresource technology, 99(14), 6656-6660 (2008-01-08)
The sesame (Sesamum indicum L.) oil was extracted from the seeds of the sesame that grows in Diyarbakir, SE Anatolia of Turkey. Sesame seed oil was obtained in 58wt/wt%, by traditional solvent extraction. The methylester of sesame (Sesamum indicum L.)
Eric W Prouty et al.
The European journal of neuroscience, 50(1), 1712-1726 (2019-01-29)
Glucocorticoid hormones and serotonin (5-HT) are strongly associated with the development and treatment of depression, respectively. Glucocorticoids regulate the function of serotonergic neurons in the dorsal raphe nucleus (DR), which are the major source of 5-HT to the forebrain. DR
Martin Höhne et al.
The American journal of pathology, 182(2), 332-338 (2012-12-19)
Podocytes, the visceral epithelial cells of the kidney glomerulus, elaborate primary and interdigitating secondary extensions to enwrap the glomerular capillaries. A hallmark of podocyte injury is the loss of unique ultrastructure and simplification of the cell shape, called foot process
Sylvia M Bardet et al.
Neuroreport, 21(5), 376-380 (2010-02-12)
It was shown earlier that, in Japanese quail the mechanism controlling the induction by testosterone of aromatase activity develops between embryonic days 10 and 14. The cellular processes underlying this activation have, however, not been investigated in detail. Here, we
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