PZ0022

BLI-489 hydrate

≥98% (HPLC)

• Synonym(s): 6-[(5,6-Dihydro-8H-imidazo[2,1-c][1,4]oxazin-2-yl)methylene]-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid sodium salt hydrate, WAY-185489
• Empirical Formula (Hill Notation): C₁₃H₁₀N₃NaO₄S · xH₂O
• CAS Number: 623564-40-9
• Molecular Weight: 327.29 (anhydrous basis)
• MDL number: MFCD22374169
• UNSPSC Code: 12352200
• PubChem Substance ID: 329823689
• NACRES: NA.77

Properties

• Quality Level: 100
• Assay: ≥98% (HPLC)
• form: powder
• color: yellow
• solubility: H₂O: >20 mg/mL
• storage temp.: room temp
• SMILES string: O.[Na+].[O-]C(=O)C1=CS[C@H]2N1C(=O)\C2=C\c3cnc4COCCn34
• InChI: 1S/C13H11N3O4S.Na.H2O/c17-11-8(12-16(11)9(6-21-12)13(18)19)3-7-4-14-10-5-20-2-1-15(7)10;;/h3-4,6,12H,1-2,5H2,(H,18,19);;1H2/q;+1;/p-1/b8-3-;;/t12-;;/m1../s1
• InChI key: UAZCFKAYAYJPDM-UVEQJXRBSA-M

Description

Biochem/physiol Actions

BLI-489 is a penem β-lactamase inhibitor, which has shown activity against class A, C, and D β-lactamases. BLI-489 is being tested in combination therapy for drug-resistant bacteria.

BLI-489 is a penem β-lactamase inhibitor.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable