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I0635

Sigma-Aldrich

4,4′-Isopropylidenediphenol

Synonym(s):

2,2-Bis(4-hydroxyphenyl)propane, Bisphenol A

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About This Item

Empirical Formula (Hill Notation):
C15H16O2
CAS Number:
Molecular Weight:
228.29
Beilstein:
1107700
EC Number:
MDL number:
UNSPSC Code:
12000000

SMILES string

CC(C)(c1ccc(O)cc1)c2ccc(O)cc2

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Signal Word

Danger

Hazard Statements

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Repr. 1B - Skin Sens. 1 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

440.6 °F - closed cup

Flash Point(C)

227 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Séverine H Collet et al.
Toxicology and applied pharmacology, 284(3), 323-329 (2015-03-12)
The investigation of interspecies differences in bisphenol A (BPA) pharmacokinetics (PK) may be useful for translating findings from animal studies to humans, identifying major processes involved in BPA clearance mechanisms, and predicting BPA PK parameters in man. For the first
Chandrew Rajakumar et al.
Reproductive toxicology (Elmsford, N.Y.), 53, 39-44 (2015-03-19)
This study examined the effect of bisphenol A (BPA) on human placental gene expression using primary trophoblast cells as an in vitro model system. Trophoblast cells were isolated from human placentas at term, cultured and then exposed to environmentally relevant
Christopher Elam et al.
European journal of medicinal chemistry, 46(5), 1512-1523 (2011-03-01)
Two screening protocols based on recursive partitioning and computational ligand docking methodologies, respectively, were employed for virtual screens of a compound library with 345,000 entries for novel inhibitors of the enzyme sarco/endoplasmic reticulum calcium ATPase (SERCA), a potential target for
Marie Tremblay-Franco et al.
PloS one, 10(10), e0141698-e0141698 (2015-10-31)
Along with the well-established effects on fertility and fecundity, perinatal exposure to endocrine disrupting chemicals, and notably to xeno-estrogens, is strongly suspected of modulating general metabolism. The metabolism of a perinatally exposed individual may be durably altered leading to a
Justine Mathieu-Denoncourt et al.
General and comparative endocrinology, 219, 53-63 (2015-02-11)
Polymer flexibility and elasticity is enhanced by plasticizers. However, plasticizers are often not covalently bound to plastics and thus can leach from products into the environment. Much research effort has focused on their effects in mammalian species, but data on

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