G6878
3-Guanidinopropionic acid
≥97.5% (TLC)
Synonym(s):
β-Guanidinopropionic acid
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About This Item
Linear Formula:
HN=C(NH2)NHCH2CH2COOH
CAS Number:
Molecular Weight:
131.13
Beilstein:
1705262
EC Number:
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.26
Pricing and availability is not currently available.
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Product Name
3-Guanidinopropionic acid,
Assay
≥97.5% (TLC)
Quality Level
form
powder or crystals
color
white
mp
222 °C (dec.) (lit.)
storage temp.
2-8°C
SMILES string
NC(=N)NCCC(O)=O
InChI
1S/C4H9N3O2/c5-4(6)7-2-1-3(8)9/h1-2H2,(H,8,9)(H4,5,6,7)
InChI key
KMXXSJLYVJEBHI-UHFFFAOYSA-N
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Biochem/physiol Actions
β-Guanidinopropionic acid is studied for potential use during protein refolding as an anti-aggregatory molecule similar to L-arginine. β-Guanidinopropionic acid may be used to study its proliferative activity for endothelial cells contributing to wound healing. β-Guanidinopropionic acid is closely related to leptin.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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A Bexfield et al.
The British journal of dermatology, 162(3), 554-562 (2009-10-06)
Maggot therapy, utilizing the larvae of Lucilia sericata, has been reported to reduce the bacterial load within wounds and also to enhance wound healing. Maggot excretions/secretions (ES) have been shown to have a role in the success of maggot therapy.
Inge Oudman et al.
PloS one, 8(1), e52879-e52879 (2013-01-18)
Creatine kinase plays a key role in cellular energy transport. The enzyme transfers high-energy phosphoryl groups from mitochondria to subcellular sites of ATP hydrolysis, where it buffers ADP concentration by catalyzing the reversible transfer of the high-energy phosphate moiety (P)
Shirin Mirshamsi et al.
Regulatory peptides, 141(1-3), 19-24 (2007-03-10)
A number of hormones, including leptin, have been shown to inhibit food intake in humans and animals. Analogues of 3-guanidinopropionic acid have also been found to reduce total food intake, but their mechanisms of action have not been well studied.
Yoshinobu Ohira et al.
Bioscience, biotechnology, and biochemistry, 75(6), 1085-1089 (2011-06-15)
The effects of supplementation with creatine (Cr) and its analog, β-guanidinopropionic acid (β-GPA), on the differentiation of myoblasts and the numbers of nucleoli were studied in C2C12 cells. The cells were cultured in differentiation medium for 4 d. Then Cr
Efraim H Rosenberg et al.
Journal of inherited metabolic disease, 29(2-3), 345-346 (2006-06-10)
In the study reported, we prove that mutations in the SLC6A8 gene are responsible for SLC6A8 deficiency, a cerebral creatine deficiency syndrome (CCDS), since overexpression of the wild-type SLC6A8 open reading frame (ORF) restores the creatine uptake profile in SLC6A8-deficient
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