A0679
3′-Azido-3′-deoxythymidine β-D-glucuronide sodium salt
≥97% (HPLC)
Synonym(s):
AZT glucuronide sodium-potassium salt
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Assay
≥97% (HPLC)
Other Notes
Glucuronide metabolite of 3′-azido-3′-deoxythymidine
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Pediatric research, 44(1), 47-53 (1998-07-17)
Zidovudine (azidothymidine, AZT) is used in pregnancy to reduce mother to infant transmission of HIV. Understanding the disposition of AZT in the fetus is necessary to optimize therapeutic regimens directed toward the fetus. Recent studies in primates found similar steady-state
Journal of chromatography. B, Biomedical sciences and applications, 726(1-2), 225-236 (1999-05-29)
A complete two-dimensional separation technique for the determination of acidic compounds in plasma was developed by using column-switching reversed-phase liquid chromatography. This technique was based on solute peak enrichment at the top of the second column during heart-cutting and an
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