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70420

Sigma-Aldrich

Naphthofluorescein

suitable for fluorescence

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About This Item

Empirical Formula (Hill Notation):
C28H16O5
CAS Number:
61419-02-1
Molecular Weight:
432.42
Beilstein:
61335
MDL number:
MFCD00329026
UNSPSC Code:
12352108
PubChem Substance ID:
57652246
NACRES:
NA.32
Pricing and availability is not currently available.

form

powder

Quality Level

100

pKa 

7.6

mp

189 °C (dec.) (lit.)

solubility

DMF: soluble
DMSO: soluble
H2O: soluble (pH ≥ 8)

fluorescence

λex 594 nm; λem 663 nm in 0.1 M Tris pH 9.0

suitability

suitable for fluorescence

SMILES string

Oc1ccc2c3Oc4c(ccc5cc(O)ccc45)C6(OC(=O)c7ccccc67)c3ccc2c1

InChI

1S/C28H16O5/c29-17-7-9-19-15(13-17)5-11-23-25(19)32-26-20-10-8-18(30)14-16(20)6-12-24(26)28(23)22-4-2-1-3-21(22)27(31)33-28/h1-14,29-30H

InChI key

IXQIUDNVFVTQLJ-UHFFFAOYSA-N

Application

suitable as pH-indicator

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

Reference standard. Long-wavelength pH-dependent spectra[1]

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCJ1165
BCCH0081
BCCG8265
BCCD6832
BCBX0357

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O.S. Wolfbeis et al.
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Julia Baumann et al.
Experimental cell research, 383(2), 111503-111503 (2019-07-25)
Hypoxic blood-brain barrier (BBB) dysfunction is a common feature of CNS diseases however mechanisms underlying barrier disturbance are still largely unknown. This study investigated the role of transforming growth factor β (TGFβ), a cytokine known to induce expression of the

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