T7891
Thiochrome
analytical standard
Synonym(s):
2,7-Dimethylthiachromine-8-ethanol
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About This Item
Empirical Formula (Hill Notation):
C12H14N4OS
CAS Number:
Molecular Weight:
262.33
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24
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Recommended Products
grade
analytical standard
Quality Level
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
format
neat
SMILES string
Cc1ncc2CN3C(C)=C(CCO)SC3=Nc2n1
InChI
1S/C12H14N4OS/c1-7-10(3-4-17)18-12-15-11-9(6-16(7)12)5-13-8(2)14-11/h5,17H,3-4,6H2,1-2H3
InChI key
GTQXMAIXVFLYKF-UHFFFAOYSA-N
Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Biochem/physiol Actions
Selective M4 muscarinic receptor enhancer of acetylcholine affinity.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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J W Brunnekreeft et al.
Journal of chromatography, 491(1), 89-96 (1989-06-30)
A liquid chromatographic method involving precolumn derivatization for determining thiamine and its phosphate esters in human blood has been optimized. Blood sample stored at - 20 degrees C were haemolysed and deproteinized by perchloric acid. The supernatants of the samples
Sung Joon Ahn et al.
The international journal of biochemistry & cell biology, 35(2), 157-167 (2002-12-14)
Effects of the coenzyme thiamine pyrophosphate and its analogs on the inhibition of self-splicing of primary transcripts of the phage T4 thymidylate synthase gene (td) were investigated. Of all compounds tested, the coenzyme thiamine pyrophosphate was the most potent inhibitor
F S Larin et al.
Ukrainskii biokhimicheskii zhurnal (1978), 58(5), 89-91 (1986-09-01)
Thiochrome caproate modified by the oxyethyl radical of the thiochrome derivative was studied for its effect on different indices of lipid metabolism in the liver and blood of albino rats. It was shown that when animals were fed on a
Hailin Zhu et al.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 19(2), 289-294 (2003-03-01)
Fluorometric determination of thiamine requires the conversion of the analyte to fluorescent thiochrome by hexacyanoferrate(III) oxidation in alkaline solution and the isolation of the produced thiochrome from the reaction medium by solvent extraction. It was observed that thiochrome could be
J Schrijver et al.
Annals of clinical biochemistry, 19(Pt 1), 52-56 (1982-01-01)
A sensitive and reliable method for the determination of total thiamine (vitamin B1) in whole blood has been developed which is suited for routine analysis. After extraction, and enzymatic hydrolysis of thiamine phosphate esters, thiamine is separated from interfering compounds
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