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Sigma-Aldrich

ECO TWEEN® 40

greener alternative

viscous liquid

Synonym(s):

TWEEN® 40, Polyoxyethylenesorbitan monopalmitate

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About This Item

CAS Number:
9005-66-7
MDL number:
MFCD00165345
UNSPSC Code:
12161902
NACRES:
NA.28

description

non-ionic

Quality Level

200

Assay

~90.0% (GC)

form

viscous liquid

mol wt

estimated mol wt 1277

composition

Palmitic acid, ~90.0% (balance primarily stearic acid)

greener alternative product characteristics

Use of Renewable Feedstocks
Design for Degradation
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

CMC

0.027 (20-25°C)

solubility

water: 100 mg/mL, clear to slightly hazy, faintly yellow

HLB

15.6

greener alternative category

, Aligned

InChI

1S/C26H50O10/c1-2-3-4-5-6-7-8-9-10-11-24(30)34-19-18-31-20-22(32-15-12-27)26-25(35-17-14-29)23(21-36-26)33-16-13-28/h22-23,25-29H,2-21H2,1H3

InChI key

HMFKFHLTUCJZJO-UHFFFAOYSA-N

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General description

ECO Tween® 40, also known as Polyoxyethylenesorbitan monopalmitate, is a bio-based, nonionic detergent manufactured from natural fatty acid (palmitic acid). This surfactant, derived from natural sources, provides various functional advantages, such as detergency, emulsification, and wetting. Its versatility makes it well-suited for a variety of applications in biochemical and biological research, with common uses including cell lysis, nuclei isolation and cell fractionation.
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. This product is a biobased surfactant and is aligned with the 7th principle of Green Chemistry "Use of Renewable Feedstocks" and the 10th principle "Design for Degradation".

Application

Non-ionic detergent used for cell lysis, nuclei isolation and cell fractionation.
Polyoxyethylenesorbitan monopalmitate, or Tween® 40, has been used in a study to assess the determination of iodide in urine based on a chemiluminescence system. It has also been used in a study to investigate the delivery of astaxanthin and canthaxanthin to HepG2 cells.

Features and Benefits

  • 100 % Renewable
  • 100 % Bio-based
  • Certified to the USDA BioPreferred Program
  • Lower carbon footprint than petrochemical-based versions
  • High-purity chemical suitable for a wide variety of research applications

Other Notes

For additional information on our range of Biochemicals, please complete this form.

Legal Information

ECO TWEEN is a registered trademark of Croda Inc.
TWEEN is a registered trademark of Croda International PLC

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

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Certificates of Analysis (COA)

Lot/Batch Number
MKCP6605

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Christine Boesch-Saadatmandi et al.
Cytotechnology, 63(1), 89-97 (2010-12-15)
The present investigation aimed to compare fetal calf serum (FCS) and Tween 40 with the commonly employed tetrahydrofuran (THF) with respect to cytotoxicity, stability of the solubilized carotenoids, and uptake and accumulation of the xanthophylls astaxanthin (AX) and canthaxanthin (CX)
Determination of iodide in urine based on chemiluminescence system of cerium (IV)-tween 40-iodide
Li and Xie
Journal of Luminescence, 132, 5-5 (2012)
Sung Bae Kim et al.
Applied biochemistry and biotechnology, 129-132, 486-495 (2006-08-19)
Methods of increasing the enzymatic digestibility of waste newspaper by adding Tween (TW)-20 and 80 surfactants were investigated. Tween-series surfactants were selected because these surfactants increase cellulase activity during enzymatic hydrolysis and do not inhibit cell growth in downstream fermentation
F Podlogar et al.
International journal of pharmaceutics, 276(1-2), 115-128 (2004-04-29)
Pharmaceutically usable microemulsion systems were prepared from water and isopropyl myristate with a constant amount of Tween 40 and Imwitor 308 at a mass ratio of 1. Their type and structure were examined by measuring density and surface tension, and
J G Culvenor et al.
Journal of cellular biochemistry, 20(2), 127-138 (1982-01-01)
Plasma membrane was isolated from the mouse T lymphoma cell line WEHI-22 using four different methods of cell disruption followed by centrifugal fractionation. Disruption by nitrogen cavitation or by shearing with a cell pump produced plasma membrane vesicles of similar
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