Components of boldness, such as activity level and locomotion, influence an individual's ability to avoid predators and acquire resources, generating fitness consequences. The presence of endocrine disrupting chemicals (EDCs) in the aquatic environment may affect fitness by changing morphology or
Since the ban on tributyltin (TBT) in 2008, dozens of alternative antifouling agents have been used instead. Unfortunately, these alternative antifouling agents contain diverse toxic components, which have contaminated the coasts. From 2006 to 2013, the concentration of chlorothalonil, dichlofluanid
Archives of toxicology, 90(3), 661-675 (2015-01-16)
Humans are simultaneously exposed to several chemicals that act jointly to induce mixture effects. At doses close to or higher than no-observed adverse effect levels, chemicals usually act additively in experimental studies. However, we are lacking knowledge on the importance
The extended one-generation reproduction toxicity study (OECD 443, adopted 28-July-2011) produces more information with fewer animals than the two-generation study (OECD 416), by including F1 neurotoxicity and immunotoxicity assessments, and omitting an F2 generation if there are no relevant F1
Proceedings of the National Academy of Sciences of the United States of America, 109(23), 9143-9148 (2012-05-23)
Ancestral environmental exposures have previously been shown to promote epigenetic transgenerational inheritance and influence all aspects of an individual's life history. In addition, proximate life events such as chronic stress have documented effects on the development of physiological, neural, and
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