Se pu = Chinese journal of chromatography, 26(6), 731-735 (2009-03-04)
A method to determine ginkgolic acids in Ginkgo biloba leaves was developed on the basis of pyrolytic methylation-gas chromatography. Pyrolytic methylation of G. biloba leaves in the injector at 300 degrees C in the presence of an organic alkali, tetramethylammonium
Ginkgolic acids (GAs), extracted from the seed coat of Ginkgo biloba L. Our previous study has shown that GA monomer could inhibit the growth of Hep-2 significantly and induce the fragmentation of the chromosomal DNA. To further assess the antitumor
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 40(3), 459-461 (2009-07-25)
To investigate the anti-cancer effects and mechanism of natural plant ginkgolic acids (GAs) on Human Hep-2 cancer cells. Hep-2 cancer cells were treated with different concentration of GAs for different times. The proliferation of Hep-2 cancer cells were detected by
Extracts of leaves of Ginkgo biloba (family Ginkgoaceae), widely used in the treatment of peripheral and cerebral circulatory disorders as well as for dementia of different aetiology, contain long chain alkylphenols (with allergenic, cytotoxic, mutagenic and tumour-promoting properties) together with
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 878(28), 2701-2706 (2010-09-11)
A highly sensitive HPLC-ESI-MS method has been developed and validated for the quantification of ginkgolic acid (15:1) in a small quantity of rat plasma (50μL) using its homologous compound ginkgolic acid (17:1) as an internal standard. GA (15:1) and GA
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