444229

MMP-8, Human Neutrophil

• Synonym(s): Matrix Metalloproteinase 8, Human Neutrophil Collagenase, Collagenase-2
• Enzyme Commission number: 3.4.24.34 (BRENDA, IUBMB)
• UNSPSC Code: 12352202
• NACRES: NA.77

Properties

• Assay: ≥90% (SDS-PAGE)
• Quality Level: 100
• form: liquid
• specific activity: ≥40 mU/mg protein
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; avoid repeated freeze/thaw cycles
• foreign activity: other MMP, none detected
• shipped in: wet ice
• storage temp.: −70°C

Description

General description

Native pro-MMP-8 from stimulated human neutrophils. MMP-8 is an N-linked, complex glycoprotein that preferentially hydrolyzes Type I collagen versus Types II and III. Activated MMP-8 is inhibited by TIMP-1. Requires activation just prior to use. MW 58800/44000.

Native pro-MMP-8 from stimulated human neutrophils. MMP-8 is an N-linked, complex glycoprotein that preferentially hydrolyzes Type I collagen versus Types II and III. Activated MMP-8 is inhibited by TIMP-1. Requires activation prior to use.

Packaging

Please refer to vial label for lot-specific concentration.

Warning

Toxicity: Standard Handling (A)

Other Notes

Deschamps, A. M., et al. 2005. Circulation111, 1166.
Mallya, S.K., et al. 1990. Biochemistry 29, 10628.
Marcy, A.I., et al. 1991. Biochemistry30, 6476.
Stricklin, et al. 1983. Biochemistry22, 61.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable