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840054P

Avanti

Soy PC

Avanti Research™ - A Croda Brand

Synonym(s):

L-α-phosphatidylcholine (Soy)

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About This Item

CAS Number:
97281-47-5
UNSPSC Code:
12352211
NACRES:
NA.25

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 g (840054P-1g)
pkg of 2 × 100 mg (840054P-200mg)
pkg of 5 × 100 mg (840054P-500mg)
pkg of 1 × 25 mg (840054P-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand

lipid type

phospholipids
phosphoglycerides

shipped in

dry ice

storage temp.

−20°C

SMILES string

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCC)=O)=O

InChI

1S/C42H80NO8P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43(3,4)5)38-48-41(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h14,16,20-21,40H,6-13,15,17-19,22-39H2,1-5H3/b16-14-,21-20-/t40-/m1/s1

InChI key

JLPULHDHAOZNQI-ZTIMHPMXSA-N

General description

Phosphatidylcholine (PC) is the main constituent of the plasma membrane. Generally, PC has unsaturated fatty acid, in both from human and vegetable origin. Fatty acid composition of soy PC has 70 % of linolenic acid. Hence, Soy PC has low phase transition temperature in water containing systems.

Application

Soy PC has been used in the preparation of liposomes. Soy PC is suitable for use in the preparation of flexible liposomes (FLUV) and in treating Pheochromocytoma (PC12) cells to analyze its effects on exocytosis kinetics.

Biochem/physiol Actions

Phosphatidylcholine is the main source of phosphocholine, which aids in transforming ceramides into sphingomyelin. Phosphatidylcholine is more prominent in the living tissues. Soy PC is commonly used in cosmetic formulations.

Packaging

5 mL Clear Glass Sealed Ampule (840054P-200mg)
5 mL Clear Glass Sealed Ampule (840054P-25mg)
5 mL Clear Glass Sealed Ampule (840054P-500mg)
60 mL Amber Wide Mouth Screw Cap Glass Bottle (840054P-1g)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Targeted antiepidermal growth factor receptor (cetuximab) immunoliposomes enhance cellular uptake in vitro and exhibit increased accumulation in an intracranial model of glioblastoma multiforme.
Mortensen J, et al.
Journal of Drug Delivery, 2013 (2013)
Phospholipid mediated plasticity in exocytosis observed in PC12 cells.
Uchiyama Y, et al.
Brain Research, 1151(1), 46-54 (2007)
Handbook of Cosmetic Science and Technology, 1151(1), 155-155 (2005)
Louiza Bohn Thomsen et al.
Materials (Basel, Switzerland), 12(21) (2019-11-07)
Magnetic nanoparticles have great prospects for drug delivery purposes, as they can be designed with various surface coatings and conjugated with drugs and targeting moieties. They also have a unique potential for precise delivery when guided by magnetic force. The
Superresolution and fluorescence dynamics evidence reveal that intact liposomes do not cross the human skin barrier.
Dreier J, et al.
PLoS ONE, 11(1), e0146514-e0146514 (2016)
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