Journal of medicinal chemistry, 45(2), 430-437 (2002-01-11)
A new series of 8-chloro-5,5-dioxoimidazo[1,2-b][1,4,2]benzodithiazine derivatives 8-25 with heteroaryloxycarbonyl or heteroarylcarbamoyl substituents at position 7 have been synthesized as potential antitumor agents. In this procedure a novel type of mixed anhydride 7 was prepared from 8-chloro-5,5-dioxoimidazo[1,2-b][1,4,2]benzodithiazine-7-carboxylic acid 6 and methanesulfonyl
The Journal of organic chemistry, 73(20), 8093-8096 (2008-09-25)
The treatment of morphinan 1 with NaH and MsCl provided very stable iminium salt 7 possessing propellane skeleton. One of the synthesized iminium salts 7, isobutyl derivative 7b, was crystallized and its structure was determined by X-ray crystallography. The natural
The Journal of neuroscience : the official journal of the Society for Neuroscience, 3(11), 2164-2171 (1983-11-01)
Excitatory postsynaptic currents (EPSCs), miniature excitatory postsynaptic currents (MEPSCs), and acetylcholine-induced current fluctuations (noise) have been studied in voltage-clamped bullfrog parasympathetic ganglion cells of the atrial septum. EPSCs were also recorded from voltage-clamped sympathetic B cells and, in general, it
The Journal of physiology, 374, 413-427 (1986-05-01)
The development of miniature end-plate currents (m.e.p.c.s) was studied in the superior oblique and interhyoideus muscles of Xenopus laevis. An analysis of m.e.p.c. decays shows that each muscle possesses its own characteristic programme of end-plate current development. In the superior
Journal of the American Chemical Society, 129(28), 8716-8723 (2007-06-22)
The one-electron reduction of methanesulfonyl chloride (MeSO2Cl) leads, in the first instance, to an electron adduct MeSO2Cl(.)(-) which lives long enough for direct detection and decays into sulfonyl radicals MeSO2(.) and Cl(-), with k = 1.5 x 10(6) s(-1). Both
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