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86778

Sigma-Aldrich

3′,3″,5′,5″-Tetrabromophenolphthalein ethyl ester

for microscopy

Synonym(s):

TBPE

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About This Item

Empirical Formula (Hill Notation):
C22H14Br4O4
CAS Number:
Molecular Weight:
661.96
Beilstein:
2228548
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

grade

for microscopy

form

solid

SMILES string

CCOC(=O)c1ccccc1\C(c2cc(Br)c(O)c(Br)c2)=C3\C=C(Br)C(=O)C(Br)=C3

InChI

1S/C22H14Br4O4/c1-2-30-22(29)14-6-4-3-5-13(14)19(11-7-15(23)20(27)16(24)8-11)12-9-17(25)21(28)18(26)10-12/h3-10,27H,2H2,1H3

InChI key

SQFXATUXPUCFFO-UHFFFAOYSA-N

Application

3′,3″,5′,5″-Tetrabromophenolphthalein ethyl ester (TBPE) is an anionic dye used as a counter ion in the spectrophotometric determination of cationic surfactants. TBPE is also used in the spectrometric determination of aliphatic primary, secondary and tertiary amines.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Simultaneous spectrophotometric analysis of aliphatic amines utilizing thermochromism of charge-transfer complexes with tetrabromophenolphthalein ethyl ester.
Sakai T, et al.
Analytical Sciences, 21(12), 1557-1560 (2005)
Simple method for spectrophotometric determination of cationic surfactants without liquid-liquid extraction.
Kamaya M, et al.
Analytica Chimica Acta, 384(2), 215-218 (1999)
Ion association titration for the determination of local anesthetics in pharmaceuticals with tetrabromophenolphthalein ethyl ester as an indicator.
T Sakai et al.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 17(9), 1105-1107 (2001-11-16)
D L Mount et al.
Bulletin of the World Health Organization, 67(3), 295-300 (1989-01-01)
Two field-adapted colorimetric methods for measuring the antimalarial drug chloroquine in urine are described. Both are modifications of the method of Saker and Solomons for screening urine for phencyclidine and other drugs of abuse, using the colour reagent tetrabromophenolphthalein ethyl
J G Rio et al.
Journal of analytical toxicology, 5(6), 267-269 (1981-11-01)
A simple direct colorimetric test using a tetrabromophenolphthalein reagent for detecting basic drugs in urine is described. The response of 62 commonly encountered drugs and metabolites to this test are described and 39 of these compounds were found to react.

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