Journal of the American Chemical Society, 133(24), 9140-9143 (2011-05-25)
Acetaldehyde is an environmentally widespread genotoxic aldehyde present in tobacco smoke, vehicle exhaust and several food products. Endogenously, acetaldehyde is produced by the metabolic oxidation of ethanol by hepatic NAD-dependent alcohol dehydrogenase and during threonine catabolism. The formation of DNA
Journal of chromatography. A, 1232, 281-287 (2012-02-22)
Carbonyl compounds are common byproducts of many metabolic processes. These volatile chemicals are usually derivatized before mass spectrometric analysis to enhance the sensitivity of their detections. The classically used reagent for this purpose is 2,4-dinitrophenylhydrazine (DNPH) that forms the corresponding
Journal of proteome research, 10(4), 1719-1727 (2011-01-18)
Oxidative stress plays a critical role in the pathogenesis of a number of diseases. The carbonyl end products of protein oxidation are among the most commonly measured markers of oxidation in biological samples. Protein carbonyl functional groups may be derivatized
Journal of hazardous materials, 179(1-3), 141-150 (2010-03-30)
Nanocrystalline Zn(2)SnO(4) microcubes were hydrothermally synthesized and systematically characterized by XRD, SEM, TEM, XPS, N(2) adsorption-desorption, and UV-vis DRS analysis. The resulting Zn(2)SnO(4) microcubes with the edge size ranging from 0.8 to 1.2 microm were composed of numerous nanoparticles with
Journal of proteomics, 74(11), 2351-2359 (2011-06-15)
Reactive oxygen species (ROS) can oxidize proteins at almost any amino acid residue. Whereas some modifications are reversible within the cells, the higher oxidation states are especially irreversible. These irreversible post translational modifications are widely used as biomarkers of oxidative
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