K401

2-Ketobutyric acid

97%

• Synonym(s): 2-Oxobutanoic acid, 2-Oxobutyric acid, α-Ketobutyric acid, Propionylformic acid
• Linear Formula: CH₃CH₂COCOOH
• CAS Number: 600-18-0
• Molecular Weight: 102.09
• Beilstein: 1700514
• EC Number: 209-986-9
• MDL number: MFCD00004164
• UNSPSC Code: 12352100
• PubChem Substance ID: 24896237
• NACRES: NA.22

Properties

• Assay: 97%
• form: liquid
• bp: 84 °C/20 mmHg (lit.)
• mp: 30-34 °C (lit.)
• storage temp.: 2-8°C
• SMILES string: CCC(=O)C(O)=O
• InChI: 1S/C4H6O3/c1-2-3(5)4(6)7/h2H2,1H3,(H,6,7)
• InChI key: TYEYBOSBBBHJIV-UHFFFAOYSA-N

Description

Application

2-Ketobutyric acid can be used as a reactant to synthesize:

• (S)-2-Aminobutyric acid via enzyme-catalyzed amination reaction.
• L-Isoleucine by living cell reaction in the presence of ethanol.
• 3-Ethyl-2-quinoxalinol from 1,2-diaminobenzene in the presence of sulfuric acid.
• 3-Ethylbenzo[g]quinoxalin-2(1H)-one using 2,3-diaminonaphthalene in the presence of biocatalyst.

Safety Information

• Pictograms: GHS05
• Signal Word: Danger
• Hazard Statements: H314
• Precautionary Statements: P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363 - P405
• Hazard Classifications: Eye Dam. 1 - Skin Corr. 1B
• Storage Class Code: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• Flash Point(F): 179.6 °F - closed cup
• Flash Point(C): 82 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves