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Sigma-Aldrich

Methoxyacetic acid

98%

Synonym(s):

NSC 7300

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About This Item

Linear Formula:
CH3OCH2COOH
CAS Number:
625-45-6
Molecular Weight:
90.08
Beilstein:
635800
EC Number:
210-894-6
MDL number:
MFCD00004308
UNSPSC Code:
12352100
PubChem Substance ID:
24851659
NACRES:
NA.22

Assay

98%

form

liquid

refractive index

n20/D 1.417 (lit.)

bp

202-204 °C (lit.)

mp

7-9 °C (lit.)

density

1.174 g/mL at 25 °C (lit.)

SMILES string

COCC(O)=O

InChI

1S/C3H6O3/c1-6-2-3(4)5/h2H2,1H3,(H,4,5)

InChI key

RMIODHQZRUFFFF-UHFFFAOYSA-N

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General description

Methoxyacetic acid is the major metabolite of ester phthalates widely used in industry as gelling, viscosity and stabilizer reagents.

Application

Methoxyacetic acid was used in zebrafish embryotoxicity test to evaluate chemical toxicity after exposure of the complete vertebrate embryo during embryogenesis in ovo.

Signal Word

Danger

Hazard Statements

H302,H314,H335,H360FD

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 1B - Skin Corr. 1B - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 2

Flash Point(F)

237.2 °F - closed cup

Flash Point(C)

114 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Bao-Lin Li et al.
Chirality, 20(1), 35-39 (2007-10-26)
The resolutions of (9-anthryl)methoxyacetic acid (9AMAA) and (9-anthryl)hydroxyacetic acid (9AHAA) were performed by capillary electrophoresis using hydroxypropyl-beta-cyclodextrin (HP-beta-CD) as a chiral selector. Various factors affecting migration time and resolutions of these compounds were investigated with a run voltage of 20
Bo Yang et al.
Urology, 81(3), 696-696 (2013-01-08)
To investigate the expression pattern of Ras-related protein 1 (Rap1) during testicular development and to clarify whether its expression is developmentally regulated and whether this expression is involved in the process of germ cell apoptosis. The expression pattern of Rap1
Gargi Bagchi et al.
Reproductive biology and endocrinology : RB&E, 9, 42-42 (2011-04-02)
Optimal androgen signaling is critical for testicular development and spermatogenesis. Methoxyacetic acid (MAA), the primary active metabolite of the industrial chemical ethylene glycol monomethyl ether, disrupts spermatogenesis and causes testicular atrophy. Transcriptional trans-activation studies have indicated that MAA can enhance
Derek V Henley et al.
Environmental health perspectives, 117(11), 1702-1706 (2010-01-06)
Ethylene glycol monomethyl ether (EGME) exposure is associated with impaired reproductive function. The primary metabolite of EGME is methoxyacetic acid (MAA), a short-chain fatty acid that inhibits histone deacetylase activity and alters gene expression. Because estrogen signaling is necessary for
Wu-Gang Hou et al.
Cell and tissue research, 337(2), 257-267 (2009-05-28)
N-Myc downstream regulated gene 2 (NDRG2) is expressed in the testis of adult animals and is involved in cell differentiation and development. However, little is known about the expression pattern of NDRG2 in the testis during postnatal development. Here, we
View All Related Papers

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