M1808000
Metixene hydrochloride
European Pharmacopoeia (EP) Reference Standard
Synonym(s):
Methixene monohydrochloride monohydrate
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About This Item
Empirical Formula (Hill Notation):
C20H23NSl · HCl · H2O
CAS Number:
UNSPSC Code:
41116107
NACRES:
NA.24
Recommended Products
grade
pharmaceutical primary standard
API family
metixene
manufacturer/tradename
EDQM
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
InChI
1S/C20H23NS.ClH.H2O/c1-21-12-6-7-15(14-21)13-18-16-8-2-4-10-19(16)22-20-11-5-3-9-17(18)20;;/h2-5,8-11,15,18H,6-7,12-14H2,1H3;1H;1H2
InChI key
RAOHHYUBMJLHNC-UHFFFAOYSA-N
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Application
Metixene hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
Packaging
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
Other Notes
Sales restrictions may apply.
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JAMA, 195(10), 851-851 (1966-03-07)
Methixene hydrochloride, an anticholinergic agent, may be useful in the symptomatic treatment of functional bowel disorders. Adverse effects reported from its use are those of the anticholinergic drugs in general.
[An anticholinergic agent, the side effect of mouth dryness and hazards for the teeth].
W H van Palenstein Helderman et al.
Nederlands tijdschrift voor geneeskunde, 127(51), 2318-2321 (1983-12-17)
M I Walash et al.
Pharmaceutisch weekblad. Scientific edition, 8(4), 234-238 (1986-08-22)
A simple and rapid colorimetric method for the quantitative determination of the thioxanthene derivatives, chlorprothixene, tiotixene and metixene has been performed either in their pure form or in tablets. The procedure is based upon the formation of charge transfer complexes
A complication of self-poisoning.
C H Gerrand et al.
Postgraduate medical journal, 73(856), 113-114 (1997-02-01)
S L Levin
International journal of clinical pharmacology research, 6(5), 429-439 (1986-01-01)
Dualism in the effects of atropine, and metixene upon the denervated human parotid salivary gland is demonstrated by the fact that they suppress pilocarpine secretion while themselves causing an extremely intense and prolonged salivation. A still stronger cholinolytic, chlorosyle, although
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