P5397

n-Propionyl coenzyme A lithium salt

≥85%

• Synonym(s): n-Propionyl CoA lithium salt
• Empirical Formula (Hill Notation): C₂₄H₄₀N₇O₁₇P₃S
• CAS Number: 108321-21-7
• Molecular Weight: 823.60
• UNSPSC Code: 41106305
• PubChem Substance ID: 24898631
• NACRES: NA.51

Properties

• biological source: yeast
• Quality Level: 200
• Assay: ≥85%
• form: powder
• solubility: H₂O: soluble-50 mg/mL, clear, colorless
• storage temp.: −20°C
• SMILES string: [Li].[P](=O)(O[P](=O)(OCC([C@@H](O)C(=O)NCCC(=O)NCCSC(=O)CC)(C)C)O)(OC[C@H]1O[C@H]([C@@H]([C@@H]1O[P](=O)(O)O)O)[n]2c3ncnc(c3nc2)N)O
• InChI: 1S/C24H40N7O17P3S.Li/c1-4-15(33)52-8-7-26-14(32)5-6-27-22(36)19(35)24(2,3)10-45-51(42,43)48-50(40,41)44-9-13-18(47-49(37,38)39)17(34)23(46-13)31-12-30-16-20(25)28-11-29-21(16)31;/h11-13,17-19,23,34-35H,4-10H2,1-3H3,(H,26,32)(H,27,36)(H,40,41)(H,42,43)(H2,

Description

General description

Propionyl-CoA is obtained as an end product of isoleucine, valine and methionine catabolism.[1] It is an essential component for the methylaspartate cycle.[2] Branched-chain amino acids and cholesterol also give rise to propionyl-CoA.[3] Propionyl coenzyme A (CoA) is the coenzyme A derivative of propionic acid.[4] Propionyl CoA is formed during the β-oxidation of odd-chain fatty acids.

Biochem/physiol Actions

Coenzyme A functions as an acyl group carrier, acetyl-CoA. Propionyl coenzyme A (Propionyl-CoA) may be used to characterize and study propionyl-coenzyme A carboxylase complexes found in bacteria. Propionyl-CoA may be used to study the specificity and kinetics of methylisocitrate lyase(s).

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves